Evidence map›Paper›PMID 35535510›Full record

ReviewJournal of cellular and molecular medicine2022

Putative therapeutic impacts of cardiac CTRP9 in ischaemia/reperfusion injury.

Seyyed-Reza Sadat-Ebrahimi, Hassan Amini, Reza Rahbarghazi, Paria Habibollahi, Shahrouz Ghaderi, Hadi Rajabi, Aysa Rezabakhsh

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Seyyed-Reza Sadat-EbrahimiCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hassan AminiDepartment of General and Vascular Surgery, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza RahbarghaziStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Paria HabibollahiDepartment of Pharmacology and Toxicology, Pharmacy Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.
Shahrouz GhaderiInstitute of Molecular Medicine III, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Hadi RajabiKoç University Research Center for Translational Medicine (KUTTAM), Koç University, School of Medicine, Istanbul, Turkey.
Aysa RezabakhshCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0003-3942-7848
Tabriz University of Medical Sciences · IRHeinrich Heine University Düsseldorf · DEKoç University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, cytokines belonging to C1q/tumour necrosis factor-related proteins (CTRPs) superfamily have attracted increasing attention due to multiple metabolic functions and desirable anti-inflammatory effects. These various molecular effectors exhibit key roles upon the onset of cardiovascular diseases, making them novel adipo/cardiokines. This review article aimed to highlight recent findings correlated with therapeutic effects and additional mechanisms specific to the CTRP9, particularly in cardiac ischaemia/reperfusion injury (IRI). Besides, the network of the CTPR9 signalling pathway and its possible relationship with IRI were discussed. Together, the discovery of all involved underlying mechanisms could shed light to alleviate the pathological sequelae after the occurrence of IRI.

Indexed as

Reperfusion InjuryHeartHumansIschemiaSignal TransductionCTRP9ischaemia/reperfusion injurysignalling pathwaystherapeutic target

Identifiers

PMID35535510
PMCPMC9170823
OpenAlexW4229447460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.