Evidence map›Paper›PMID 35535360›Full record

ArticleOxidative medicine and cellular longevity2022

Effects of Prolonged Exposure to Hypobaric Hypoxia on Oxidative Stress: Overwintering in Antarctic Concordia Station.

Simona Mrakic-Sposta, Michela Montorsi, Simone Porcelli, Mauro Marzorati, Beth Healey, Cinzia Dellanoce, Alessandra Vezzoli

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. [Mechanisms of 6-Hydroxygen Genistein in the Treatment of Pulmonary Injury in High-Altitude Hypoxic Mice].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
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  12. Oxy-Inflammation in Humans during Underwater Activities.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Simona Mrakic-SpostaInstitute of Clinical Physiology-Milan, National Research Council (CNR), Italy.ORCID https://orcid.org/0000-0001-7359-2690
Michela MontorsiDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Milan, Italy.ORCID https://orcid.org/0000-0001-5152-761X
Simone PorcelliInstitute of Biomedical Technologies, National Research Council (CNR), Segrate, Milano, Italy.
Mauro MarzoratiInstitute of Biomedical Technologies, National Research Council (CNR), Segrate, Milano, Italy.
Beth HealeyBiomedical Research, European Space Agency, Concordia, Canada.
Cinzia DellanoceInstitute of Clinical Physiology-Milan, National Research Council (CNR), Italy.
Alessandra VezzoliInstitute of Clinical Physiology-Milan, National Research Council (CNR), Italy.
National Research Council · ITCanadian Space Agency · CAInstitute of Biomedical Technologies · ITSan Raffaele University of Rome · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Concordia Station is the permanent, research station on the Antarctic Plateau at 3230 m. During the eleventh winter-over campaign (DC11-2015; February 2015 to November 2015) at Antarctic Concordia Station, 13 healthy team members were studied and blood samples were collected at six different time points: baseline measurements (T0), performed at sea level before the departure, and during the campaign at 3, 7, 20, 90, and 300 days after arrival at Concordia Station. Reducing the partial pressure of O

Indexed as

HypoxiaOxidative StressAntarctic RegionsHumansOxygenReactive Oxygen SpeciesOxygenReactive Oxygen Species

Identifiers

PMID35535360
PMCPMC9078816
OpenAlexW4225136377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.