ArticleNeurobiology of stress2022
Connecting the biology of stress, allostatic load and epigenetics to social structures and processes.
Article in Neurobiology of stress, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Allostatic Load and Cardiovascular Disease: A Systematic Review.American journal of preventive medicine · 2025Pooled it
- Allostatic load index across the psychosis spectrum: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Substance use and epigenetic age acceleration: Associations with alcohol, tobacco, illicit drugs, and SUD severity.Drug and alcohol dependence · 2026Article
- The exposome of brain aging across 34 countries.Nature medicine · 2026Article
- Real-world generalizability of clinical trial cytomolecular risk in pediatric acute myeloid leukemia: a report from the REAL-AML cohort.Journal of the National Cancer Institute · 2026Article
- Adrenarche as a regulator of sensitivity to early adversity.Journal of neuroendocrinology · 2026Review
- Psychosocial stressors, accelerated biological aging, and multiple morbidities: Evidence from an age-diverse sample.PloS one · 2026Article
- Combined intervention program of serious virtual reality games focused on controllability and Stress Inoculation Training in patients with major depression.Frontiers in psychiatry · 2026Article
- Computational whole-body-exposome models for global precision brain health.Nature communications · 2025Article
- The role of stress proliferation in linking childhood stressors to accelerated biological aging.Social science & medicine (1982) · 2025Article
- Estimating the burden of chronic stress through allostatic load in patients with chronic myeloid leukemia.Leukemia · 2025Article
- From adaptation to exhaustion: defining exposure-related malnutrition as a bioenergetic phenotype of aging.Biogerontology · 2025Review
- Discussing the Interplay of Social Determinants of Health, Aging, and Alzheimer's Biomarkers in U.S. Latinos.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Review
- Review
- What Is Social Connection in the Context of Human Need: An Interdisciplinary Literature Review.International journal of environmental research and public health · 2025Review
- Allostatic Interoceptive Overload Across Psychiatric and Neurological Conditions.Biological psychiatry · 2025Review
- The Social Context of Pregnancy, Respectful Maternity Care, Biomarkers of Weathering, and Postpartum Mental Health Inequities: A Scoping Review.International journal of environmental research and public health · 2024Article
- Differential Associations of Adversity Profiles with Adolescent Cognitive Control and Psychopathology.Research on child and adolescent psychopathology · 2023Article
- Special issue dedicated to Dr. Bruce S. McEwen.Neurobiology of stress · 2023Article
- Vitality Revisited: The Evolving Concept of Flourishing and Its Relevance to Personal and Public Health.International journal of environmental research and public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How do sociology and stress biology connect in efforts to understand the impact of early childhood adversity on health and life chances? This memorial article describes the collaboration between Bruce and Craig McEwen in bringing stress neurobiology to sociologists. It attempts, in turn, to bring sociology to stress neurobiologists, the second goal of this collaboration. It frames the social sources of human stress in terms of the social determinants of health as well as more proximal childhood adversities. It also underlines the importance of supportive adult and community relationships in preventing toxic stress. Bruce was hopeful that stress biology research could inform public health efforts aimed at improving population health and more equitable life trajectories. To strengthen our understanding of stress and to contribute to that goal, stress neurobiologists can help tease out the complex social causes of stress by expanding the range of variables employed to identify its sources as well as the protections against it in human populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.