Evidence map›Paper›PMID 35535228›Full record

ArticleComputational and mathematical methods in medicine2022

Correlation of Serum IL-18, BDNF, and IL-1

Nan Zhao, Chengcheng Dong

RetractedAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Frontiers in pharmacology · 2022
    Article
  3. Retracted: Correlation of Serum IL-18, BDNF, and IL-1Computational and mathematical methods in medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nan ZhaoDepartment of Respiration, The First Affiliated Hospital of Harbin Medical University, 150001 Harbin City, Heilongjiang Province, China.ORCID https://orcid.org/0000-0001-8080-5834
Chengcheng DongDepartment of Respiration, The First Affiliated Hospital of Harbin Medical University, 150001 Harbin City, Heilongjiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the correlation of serum IL-18, BDNF, and IL-1 Methods: By means of retrospective analysis, the data of 240 patients at the acute exacerbation of COPD treated in our hospital (February 2018-February 2021) were analyzed. All patients received conventional treatment 1 d after admission, patients' serological indicators were measured before treatment, and after 30 d of follow-up, the patients were divided into the survival group (SG) and death group (DG) according to their clinical outcomes, the Beck's Depression Inventory (BDI) scores of the surviving patients were investigated, the correlation of IL-18, BDNF, and IL-1 Results: The results of 30 d follow-up showed that 220 patients survived (91.7%) and 20 patients died (8.3%). Among the surviving patients, 95 patients had depression and 125 patients did not have depression; the BDI scores of the depressed subjects and the nondepressed subjects were 10.35 ± 1.25 points and 2.06 ± 0.76 points, respectively; significant differences in IL-18, BDNF, and IL-1 Conclusion: In regard to the depression in COPD patients after acute exacerbation, IL18 and IL-1

Indexed as

Brain-Derived Neurotrophic FactorDepressionInterleukin-18Interleukin-1betaPulmonary Disease, Chronic ObstructiveHumansPrognosisRetrospective StudiesBDNF protein, humanBrain-Derived Neurotrophic FactorIL18 protein, humanIL1B protein, humanInterleukin-18Interleukin-1beta

Identifiers

PMID35535228
PMCPMC9078809

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.