ArticleNeuropsychiatric disease and treatment2022
Serum Calcium Levels and in-Hospital Infection Risk in Patients with Acute Ischemic Stroke.
Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Development and validation of a novel model based on hematological biomarkers for predicting risk factors and outcomes in cancer patients with carbapenem-resistant organism infection.Frontiers in public health · 2026Article
- Machine learning-based prediction of bloodstream infection in rectal carbapenem-resistantFrontiers in cellular and infection microbiology · 2026Article
- Prediction of bloodstream infection using machine learning based primarily on biochemical data.Scientific reports · 2025Article
- Risk factors of stroke-associated pneumonia in patients with acute ischemic stroke treated by endovascular thrombectomy.BMC neurology · 2025Article
- Integrating phase-rectified signal averaging with machine learning to predict stroke-associated infections: a retrospective cohort study.Frontiers in neurology · 2025Article
- Identification of risk factors and construction of a nomogram predictive model for post-stroke infection in patients with acute ischemic stroke.World journal of clinical cases · 2024Article
- Association between serum calcium and prognosis in patients with acute ischemic stroke in ICU: analysis of the MIMIC-IV database.BMC anesthesiology · 2024Article
- Serum calcium is associated with sudden cardiac arrest in stroke patients from ICU: a multicenter retrospective study based on the eICU collaborative research database.Scientific reports · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Stroke-associated infection (SAI) is one of the most common post-stroke complications, which may lead to a relatively poor prognosis. This study aims to explore the potential relationship between serum calcium levels and SAI. Patients and Methods: This is a cross-sectional study involving 395 participants. SAI is a term that covers stroke-associated pneumonia (SAP), urinary tract infection (UTI), as well as other infections diagnosed during the first week after a stroke. Serum calcium levels were measured within 24 hrs of admission. To determine the association of serum calcium levels with the SAI, logistic regression models were calculated. An adjusted spline regression model was used to further confirm the relationship between the two. Results: Among the total patients, SAI occurred in 107 (27.1%) patients. Serum calcium was associated with SAI and was independent of the SAI risk factors for age, admission NIHSS score, and intravascular therapy [adjusted OR 0.040 (95% CI = 0.005-0.291), p = 0.002]. Remarkably, this trend applies predominantly to serum calcium levels less than 2.25mmol/L (p= 0.005 for linearity). Conclusion: Serum calcium levels are associated with the risk of SAI, when serum calcium is below normal (2.25mmol/L), the risk of SAI increases as serum calcium levels decrease.
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