Evidence map›Paper›PMID 35535117›Full record

ArticleCase reports in obstetrics and gynecology2022

More than an Incidentaloma: The Nonreportable NIPT.

Allison M Jay, Brian Mason, Daniel Lebovic, Paul Chuba

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in obstetrics and gynecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Allison M JayAscension St. John Genetics, 19229 Mack Ave, Grosse Pointe, MI 48236, USA.ORCID https://orcid.org/0000-0003-2252-6954
Brian MasonAscension St. John Obstetrics and Gynecology, 22151 Moross Rd I, Suite, Grosse Pointe, MI 48236, USA.
Daniel LebovicAscension St. John, Hematology and Oncology, 19229 Mack Ave, Grosse Pointe, MI 48236, USA.
Paul ChubaAscension St. John Macomb, Radiation Oncology, 11800 Twelve Mile Rd, Warren, MI 48093, USA.ORCID https://orcid.org/0000-0002-4423-3899
Ascension · USSt. John Macomb Oakland Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive prenatal testing (NIPT), which utilizes a maternal blood sample to detect fetal gender and screen for fetal aneuploidy (abnormal chromosomes), is widely used in obstetrics to screen for Trisomies 21, 18, and 13. Per the literature, approximately 0.3% of pregnant woman's results are nonreportable. Reasons include low fetal fraction, insufficient DNA, vanishing twin, twin pregnancy, clonal mosaicism, and maternal neoplasia. Here, we describe a 25-year-old G2P1 pregnant woman who had two nonreportable NIPT results and subsequently was diagnosed with lymphoma. We discuss the importance of clinical exam in correlation with the results to offer comprehensive evaluation of the patient with a nonreportable finding, given malignancy occurs in 1/1000 pregnant women. This report overviews proposed management guidelines for pregnant women with a nonreportable result and helps to address discomfort the treating physician may feel in discussing this result with their patient.

Identifiers

PMID35535117
PMCPMC9078803
OpenAlexW4225259259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.