Evidence map›Paper›PMID 35535116›Full record

ReviewJournal of clinical and experimental hepatology

An Approach to the Management of Diabetes Mellitus in Cirrhosis: A Primer for the Hepatologist.

Pankaj Puri, Narendra Kotwal

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis (2024).Journal of clinical and translational hepatology · 2025
    Article
  10. Review
  11. [Chinese guidelines on the management of hepatic encephalopathy in cirrhosis (2024)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pankaj PuriFortis Escorts Liver and Digestive Diseases Institute, New Delhi, 110025, India.
Narendra KotwalArmed Forces Clinic, New Delhi, 110011, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of diabetes in cirrhosis and liver transplantation can be challenging. There is difficulty in diagnosis and monitoring of diabetes as fasting blood sugar values are low and glycosylated hemoglobin may not be a reliable marker. The challenges in the management of diabetes in cirrhosis include the likelihood of cognitive impairment, risk of hypoglycemia, altered drug metabolism, frequent renal dysfunction, risk of lactic acidosis, and associated malnutrition and sarcopenia. Moreover, calorie restriction and an attempt to lose weight in obese diabetics may be associated with a worsening of sarcopenia. Many commonly used antidiabetic drugs may be unsafe or be associated with a high risk of hypoglycemia in cirrhotics. Post-transplant diabetes is common and may be contributed by immunosuppressive medication. There is inadequate clinical data on the use of antidiabetic drugs in cirrhosis, and the management of diabetes in cirrhosis is hampered by the lack of guidelines focusing on this issue. The current review aims at addressing the practical management of diabetes by a hepatologist.

Indexed as

ADA, American Diabetes AssociationAGI, Alfa Glucosidase inhibitorsantidiabetic agentsantihyperglycemic drugsBMI, Body mass indexchronic liver diseasecirrhosisCLD, Chronic liver diseaseCYP-450, Cytochrome P-450diabetes mellitusDipeptidyl-peptidase 4, DPP-4eGFR, estimated glomerular filtration ratesGLP-1, Glucagon-like peptide-1HbA1c, Hemoglobin A1cHCC, Hepatocellular carcinomaHCV, Hepatitis C virusIGF, Insulin-like growth factorMALA, Metformin-associated lactic acidosisNASH, Nonalcoholic steatohepatitisNPL, Neutral protamine lisproOGTT, Oral glucose tolerance testSMBG, Self-monitoring of blood glucoseSodium-glucose cotransporter 2, SGLT2VEGF, Vascular endothelial growth factor

Identifiers

PMID35535116
PMCPMC9077234
OpenAlexW3200977848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.