Evidence map›Paper›PMID 35535070›Full record

ArticleJournal of clinical and experimental hepatology

First Report of a Paediatric Collision Tumour in the Liver Recognised After Liver Transplantation: Blissful Ignorance Has Benefits!

Sathish K Krishnan, Karattupalayam S Mouleeswaran, Prasanna Gopal, Rajanikanth Patcha, Somashekara H Ramakrishna, Perumal Karnan, Selvakumar Malleeswaran, Joy Varghese, Mettu S Reddy

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In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sathish K KrishnanDepartment of Liver Transplant and Hepatopancreatico Biliary Surgery, Gleneagles Global Health City, Chennai, India.
Karattupalayam S MouleeswaranDepartment of Pathology, Gleneagles Global Health City, Chennai, India.
Prasanna GopalDepartment of Liver Transplant and Hepatopancreatico Biliary Surgery, Gleneagles Global Health City, Chennai, India.
Rajanikanth PatchaDepartment of Liver Transplant and Hepatopancreatico Biliary Surgery, Gleneagles Global Health City, Chennai, India.
Somashekara H RamakrishnaDepartment of Peadiatric Hepatology and Pediatric Intensive Care, Gleneagles Global Health City, Chennai, India.
Perumal KarnanDepartment of Peadiatric Hepatology and Pediatric Intensive Care, Gleneagles Global Health City, Chennai, India.
Selvakumar MalleeswaranDepartment of Liver Anaesthesia and Critical Care, Gleneagles Global Health City, Chennai, India.
Joy VargheseDepartment of Hepatology and Liver Transplant, Gleneagles Global Health City, Chennai, India.
Mettu S ReddyDepartment of Liver Transplant and Hepatopancreatico Biliary Surgery, Gleneagles Global Health City, Chennai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver tumours are uncommon in the paediatric population, constituting 1-2 % of all paediatric tumours and 4% of all paediatric liver tumours. Hepatoblastoma followed by hepatocellular carcinoma is the most common tumours in this age group. Simultaneous development of two discrete liver tumours of distinct histologies (collision tumour) has been occasionally reported in adults but never in children. We hereby present the first reported case of hepatic collision tumours (hepatocellular carcinoma and cholangiocarcinoma) in the explant liver of a child who underwent living donor liver transplantation for end-stage liver disease and severe hepatopulmonary syndrome. The manuscript describes the clinical, radiological and histopathological findings of this case and also highlights the dilemma associated with management of this case had the diagnosis been made in the preoperative setting and also about the proposed management plan for this case in the postoperative period.

Indexed as

AFP, alpha fetoproteinCA 19-9, carbohydrate antigenCC, cholangiocarcinomaCECT, contrast-enhanced computed tomographycholangiocarcinomaCk, cytokeratincollision tumourCPAP, continuous positive airway pressureHCC, hepatocellular carcinomahepatocellular carcinomaHPS, hepatopulmonary syndromeLDLT, living donor liver transplantationliver transplantLT, liver transplantMAA scan, macro albumin aggregate scanpaediatric liver transplantPELD, pediataric end-stage liver disease scorePOD, postoperative dayUCSF, University of California San FranciscoUGI, upper gastrointestinal

Identifiers

PMID35535070
PMCPMC9077198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.