Evidence map›Paper›PMID 35535025›Full record

ArticleThe Journal of infectious diseases2022

Head-to-Head Comparison of Bi- and Nonavalent Human Papillomavirus Vaccine-Induced Antibody Responses.

Laila Sara Arroyo Mühr, Carina Eklund, Camilla Lagheden, Tiina Eriksson, Ville N Pimenoff, Penelope Gray, Matti Lehtinen, Joakim Dillner

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laila Sara Arroyo MührDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Carina EklundDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Camilla LaghedenDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Tiina ErikssonFinnish Cancer Centre-Mid Finland, Tampere University Hospital, Tampere, Finland.
Ville N PimenoffDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Penelope GrayFaculty of Social Sciences, Tampere University, Tampere, Finland.
Matti LehtinenDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Joakim DillnerDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For head-to-head comparison of human papillomavirus (HPV) antibody levels induced by different vaccines, 25-year-old vaccine-naive women were given either the bivalent (n = 188) or the nonavalent HPV vaccine (n = 184). Six months after vaccination antibodies against pseudovirions from 17 different HPV types (HPV6/11/16/18/31/33/35/39/45/51/52/56/58/59/66/68/73) were measured. Antibodies against HPV16/18 were higher after bivalent HPV vaccination (mean international units [IU] 1140.1 and 170.5 for HPV16 and 18, respectively) than after nonavalent vaccination (265.1 and 22.3 IUs, respectively). The bivalent vaccine commonly induced antibodies against the nonvaccine HPV types 31/33/35/45 or 58. The nonavalent vaccine induced higher antibodies against HPV6/11/31/33/45/52/58 and 35.

Indexed as

AlphapapillomavirusPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsAdultAntibodies, ViralAntibody FormationFemaleHuman papillomavirus 16Human papillomavirus 18HumansPapillomaviridaeVaccines, CombinedAntibodies, ViralPapillomavirus VaccinesVaccines, Combinedantibodybivalenthuman papillomavirusinternational unitsnonavalentvaccine

Identifiers

PMID35535025
PMCPMC9518834

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.