Evidence map›Paper›PMID 35534909›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2022

Eight tips for the implementation of the first licenced peanut allergy oral immunotherapy into clinical practice.

Jay Portnoy, Christina E Ciaccio, Janet Beausoleil, George Du Toit, Stanley Fineman, Stephen A Tilles, June Zhang, Claire Lawrence, Mohamed Yassine, S Shahzad Mustafa

Open access · goldAbstract read
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Goldilocks zone: Allergists' perceptions of family anxiety and investment in food allergy oral immunotherapy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Jay PortnoySection of Allergy, Asthma & Immunology. Children's Mercy Hospital, Kansas City, MO, United States.
Christina E CiaccioSection of Allergy/Immunology and Pediatric Pulmonology, The University of Chicago, Chicago, IL, United States.
Janet BeausoleilDivision of Allergy and Immunology, The Children's Hospital of Philadelphia, Philadelphia, United States.
George Du ToitDepartment of Women and Children's Health (Pediatric Allergy, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Stanley FinemanDivision of Allergy & Immunology, Emory University School of Medicine, Atlanta Allergy & Asthma, GA, Atlanta, United States.
Stephen A TillesAimmune Therapeutics, a Nestlé Health Science Company, 8000 Marina Blvd. Suite 300, Brisbane, CA, 94005, United States. stilles@aimmune.com.
June ZhangLatitude Food Allergy Care, Redwood City, CA, United States.
Claire LawrenceAcaster Lloyd Consulting Ltd, London, UK.
Mohamed YassineAimmune Therapeutics, a Nestlé Health Science Company, 8000 Marina Blvd. Suite 300, Brisbane, CA, 94005, United States.
S Shahzad MustafaDivision of Allergy, Immunology, and Rheumatology Rochester Regional Health, School of Medicine and Dentistry, University of Rochester, Rochester, United States.
Nestlé Health Science (United States)Children's Hospital of Philadelphia · USChildren's Mercy Hospital · USEmory University · USGuy's and St Thomas' NHS Foundation Trust · GBLatitude Pharmaceuticals (United States) · USLloyd's · GBUnity Health System · USUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShared learnings from the early use of novel therapies can aid in their optimization. The recent introduction of peanut oral immunotherapy (peanut OIT; Palforzia [Peanut (Arachis hypogaea) Allergen Powder-dnfp]) for peanut allergy addresses a significant unmet need but also highlights the requirement for consideration of several factors by both prescribers and patients.

objectiveTo provide guidance for prescribers of licenced peanut OIT to facilitate treatment delivery and improve outcomes.

methodsClinicians with experience of licenced peanut OIT (United States n = 6, United Kingdom n = 1) participated in a series of interviews and group discussions designed to elicit tips for successful implementation.

resultsClinicians identified 8 tips that were considered the most relevant, practical, and impactful for prescribers of Peanut (Arachis hypogaea) Allergen Powder-dnfp: (1) preparing to provide treatment, (2) assessing the medical indication for treatment and (3) shared decision making, (4) staff education, (5) establishing office processes, (6) managing patient expectations and using anticipatory guidance, (7) optimising adherence and (8) maintaining flexibility throughout the treatment process. In addition, a range of supporting materials (e.g., checklists and action plans) are provided.

conclusionThe introduction of a novel therapy often requires healthcare providers to modify or adopt practices to effectively employ the treatment. The provision of guidance based upon early real-world experiences of licenced peanut OIT may help inform clinical practice and improve treatment outcomes.

Indexed as

AdherenceAllergy immunotherapyDesensitizationEducationFood allergy treatmentImplementationOral immunotherapyPeanut allergyPeanut oral immunotherapyShared decision making

Identifiers

PMID35534909
PMCPMC9088027
OpenAlexW4229451953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.