Trial reportESC heart failure2022
Home-based cardiac rehabilitation using information and communication technology for heart failure patients with frailty.
Trial report in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05989594 (A Home-based Mobile Guided Exercise-based Cardiac Rehabilitation Among Patients Undergoing Transcatheter Aortic Valve Replacement), which is not on this map. Cited by 64 papers, 13 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Home-based Mobile Guided Exercise-based Cardiac Rehabilitation Among Patients Undergoing Transcatheter Aortic Valve Replacement (REHAB-TAVR): a Randomized Clinical Trial
Who cites it
64 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Digital Health Technology for Improving Physical Function in Adults With Chronic Heart Failure: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Effects of Remote, Virtual, or Hybrid Cardiac Rehabilitation Supported by mHealth in Patients With Heart Failure: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2026Pooled it
- Efficacy stratification of digital health modalities in home-based cardiac rehabilitation for heart failure: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Engaging Patients with Heart Failure in Diet and Nutritional Health Behaviors Through mHealth Applications - A Restricted, Systematic Review.Current heart failure reports · 2026Pooled it
- Application of the integrated rehabilitation-clinical-nutrition management model in geriatric rehabilitation patients: a narrative review.Frontiers in public health · 2026Pooled it
- Integrating exercise and nutrition to combat frailty: a systematic review of multidomain interventions in aging populations.Frontiers in nutrition · 2026Pooled it
- Use of mHealth Technology for Improving Exercise Adherence in Patients With Heart Failure: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Effects of exercise based cardiac rehabilitation delivery modes on chronic heart failure: a systematic review and network meta-analysis.Scientific reports · 2024Pooled it
- Effectiveness and Feasibility of Telehealth-Based Dietary Interventions Targeting Cardiovascular Disease Risk Factors: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Digital health intervention in patients undergoing cardiac rehabilitation: systematic review and meta-analysis.F1000Research · 2024Pooled it
- Systematic Review of the Association of the Hospital Frailty Risk Score with Mortality in Patients with Cerebrovascular and Cardiovascular Disease.Current cardiology reviews · 2024Pooled it
- Pooled it
- Benefits and Harms of Digital Health Interventions Promoting Physical Activity in People With Chronic Conditions: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2023Pooled it
- Improving therapeutic outcomes in heart failure with reduced nonvalvular ejection fraction: A clinical study of heart failure education intervention.Clinical cardiology · 2024Trial
- Efficacy of a cardiac rehabilitation program in a municipal sports center compared to the hospital program: randomized controlled trial eCARCEX.Anales del sistema sanitario de Navarra · 2023Trial
- Home-based cardiac rehabilitation using information and communication technology for heart failure patients with frailty.ESC heart failure · 2022Trial
- Mapping interventions addressing frailty and associated outcomes in people with heart failure: a scoping review.BMJ open · 2026Article
- Coronary artery bypass grafting patients' preferences and willingness to pay for remote cardiac rehabilitation: discrete choice experiment study.BMC health services research · 2026Article
- Knowledge, attitudes and practices towards cardiac rehabilitation among patients with heart failure.BMC public health · 2026Article
- Wearable devices and cardiovascular health: revolutionizing remote monitoring and disease prevention.European heart journal · 2026Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsCardiac rehabilitation (CR) is an evidence-based, secondary preventive strategy that improves mortality and morbidity rates in patients with heart failure (HF). However, the implementation and continuation of CR remains unsatisfactory, particularly for outpatients with physical frailty. This study investigated the efficacy and safety of a comprehensive home-based cardiac rehabilitation (HBCR) programme that combines patient education, exercise guidance, and nutritional guidance using information and communication technology (ICT). METHODS AND
resultsThis study was a single-centre, open-label, randomized, controlled trial. Between April 2020 and November 2020, 30 outpatients with chronic HF (New York Heart Association II-III) and physical frailty were enrolled. The control group (n = 15) continued with standard care, while the HBCR group (n = 15) also received comprehensive, individualized CR, including ICT-based exercise and nutrition guidance using ICT via a Fitbit® device for 3 months. The CR team communicated with each patient in HBCR group once a week via the application messaging tool and planned the training frequency and intensity of training individually for the next week according to each patient's symptoms and recorded pulse data during exercise. Dietitians conducted a nutritional assessment and then provided individual nutritional advice using the picture-posting function of the application. The primary outcome was the change in the 6 min walking distance (6MWD). The participants' mean age was 63.7 ± 10.1 years, 53% were male, and 87% had non-ischaemic heart disease. The observed change in the 6MWD was significantly greater in the HBCR group (52.1 ± 43.9 m vs. -4.3 ± 38.8 m; P < 0.001) at a 73% of adherence rate. There was no significant change in adverse events in either group.
conclusionsOur comprehensive HBCR programme using ICT for HF patients with physical frailty improved exercise tolerance and improved lower extremity muscle strength in our sample, suggesting management with individualized ICT-based programmes as a safe and effective approach. Considering the increasing number of HF patients with frailty worldwide, our approach provides an efficient method to keep patients engaged in physical activity in their daily life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.