Evidence map›Paper›PMID 35534904›Full record

ArticleTrials2022

Resources for Enhancing Alzheimer's Caregiver Health in Vietnam (REACH VN): study protocol for a cluster randomized controlled trial to test the efficacy of a family dementia caregiver intervention in Vietnam.

Duyen Tran, Huong Nguyen, Thang Pham, Anh T Nguyen, Hung T Nguyen, Ngoc B Nguyen, Bien H Nguyen, Danielle Harvey, Laura Gitlin, Ladson Hinton

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04542317 (Cluster Randomized Controlled Trial to Test the Efficacy of a Psychosocial Intervention), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04542317 nacompletednot on this map

Cluster Randomized Controlled Trial to Test the Efficacy of a Psychosocial Intervention (REACH VN) to Support Alzheimer's Family Caregivers in Vietnam

TypeinterventionalSponsorUniversity of California, DavisRan2020 to 2024Enrolled350ConditionsDementiaArmsREACH VN, Enhanced control
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Testing the Efficacy of a Culturally Adapted Family Dementia Caregiver Intervention (REACH VN): Results From a Cluster Randomized Controlled Trial in Northern Vietnam.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Duyen TranDepartment of Neurology, University of California, Davis, Sacramento, CA, USA.
Huong NguyenSchool of Nursing, University of Minnesota, Minneapolis, MN, USA.
Thang PhamNational Geriatric Hospital, Hanoi, Vietnam.
Anh T NguyenNational Geriatric Hospital, Hanoi, Vietnam.
Hung T NguyenNational Geriatric Hospital, Hanoi, Vietnam.
Ngoc B NguyenNational Geriatric Hospital, Hanoi, Vietnam.
Bien H NguyenHai Duong Provincial General Hospital, Hai Duong, Vietnam.
Danielle HarveyDepartment of Public Health Sciences, University of California, Davis, Davis, CA, USA.
Laura GitlinCollege of Nursing and Health Professions, Drexel University, Philadelphia, PA, USA.
Ladson HintonDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, 2230 Stockton Blvd, Sacramento, CA, 95817, USA. lwhinton@ucdavis.edu.ORCID http://orcid.org/0000-0002-2285-6884
University of California, Davis · USHanoi Medical University · VNUniversity of Minnesota · USDrexel University · USUniversity of Hai Duong · VNVietnam National Children's Hospital · VN

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEE-WAY JIN · 2021 to 2026
$25.2M
Advancing Alzheimer’s family caregiving interventions and research capacity in VietnamR01AG064688 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HINTON, WALTER LADSON, NGUYEN, HUONG · 2019 to 2023
$3.4M
NCATS NIH HHS UL1 TR001860NCATS NIH HHS UL1TR001860NIA NIH HHS P30 AG072972NIA NIH HHS R01 AG064688NIA NIH HHS R01AG064688
6 · The paper itself

Abstract

backgroundAlzheimer's disease and related dementias (AD/ADRD) are a public health challenge for Vietnam because of its rapidly aging population. However, very few community-based programs exist to support people living with AD/ADRD and their family caregivers. Resources for Enhancing Alzheimer's Caregiver Health in Vietnam (REACH VN) is a culturally adapted family caregiver intervention shown in a pilot study to be feasible and promising in terms of preliminary efficacy. We describe the protocol for a larger cluster randomized controlled trial (RCT) to test the efficacy of REACH VN among family caregivers of people living with dementia in a semi-rural area outside of Hanoi, Vietnam.

methodsThirty-two clusters with approximately 350 caregivers will be randomized to either REACH VN intervention or enhanced usual care. REACH VN is a multicomponent intervention delivered in-home or by phone over the course of 2 to 3 months. To be eligible, family caregivers need to be ≥18 years old, be the person who provides the most day-to-day care for people living with dementia, and have a score ≥ 6 on the Zarit Burden Interview-4. The primary outcomes are caregiver burden (Zarit Burden Interview-12) and psychological distress (Patient Health Questionnaire-4). Secondary outcomes include caregiver somatic symptoms (Patient Health Questionnaire-15) and perceived stress (Perceived Stress Scale-10). These outcomes will be assessed at baseline, 3 months, and 6 months. Exploratory analyses to examine potential mediators of primary outcomes are also planned. DISCUSSION: To our knowledge, this is the first large-scale study to test the efficacy of a community-based family dementia caregiver intervention in Vietnam. Results from this study will help inform efforts to widely deliver the REACH VN intervention or similar community-based family dementia caregiver support programs in Vietnam and other low- and middle-income countries (LMIC).

trial registrationClinicalTrials.gov NCT04542317 . Registered on 9 September 2020.

Indexed as

Alzheimer DiseaseCaregiversAdolescentAgedHumansQuality of LifeRandomized Controlled Trials as TopicVietnamAlzheimer’sDementiaFamily caregivingGlobal healthNon-pharmacological caregiving interventionVietnam

Identifiers

PMID35534904
PMCPMC9081958
OpenAlexW4229366426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.