Evidence map›Paper›PMID 35534813›Full record

ArticleBMC musculoskeletal disorders2022

A multicentre validation study of a smartphone application to screen hand arthritis.

Mark Reed, Broderick Rampono, Wallace Turner, Andreea Harsanyi, Andrew Lim, Shereen Paramalingam, David Massasso, Vivek Thakkar, Maninder Mundae, Elliot Rampono

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Smartphone-Based Hand Function Assessment: Systematic Review.Journal of medical Internet research · 2024
    Pooled it
  2. Observer: creation of a novel multimodal dataset for outpatient care research.Journal of the American Medical Informatics Association : JAMIA · 2026
    Article
  3. Article
  4. Observer: Creation of a Novel Multimodal Dataset for Outpatient Care Research.medRxiv : the preprint server for health sciences · 2025
    Article
  5. Review
  6. Article
  7. Management of Rheumatoid Arthritis in Primary Care: A Scoping Review.International journal of environmental research and public health · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Mark Reed, Perth, Australia. mark.reed@nd.edu.au.
Broderick Rampono, Perth, Australia.
Wallace Turner, Perth, Australia.
Andreea Harsanyi, Perth, Australia.
Andrew Lim, Perth, Australia.
Shereen Paramalingam, Perth, Australia.
David Massasso, Sydney, Australia.
Vivek Thakkar, Sydney, Australia.
Maninder Mundae, Melbourne, Australia.
Elliot Rampono, Perth, Australia.
Hollywood Private Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArthritis is a common condition, and the prompt and accurate assessment of hand arthritis in primary care is an area of unmet clinical need. We have previously developed and tested a screening tool combining machine-learning algorithms, to help primary care physicians assess patients presenting with arthritis affecting the hands. The aim of this study was to assess the validity of the screening tool among a number of different Rheumatologists.

methodsTwo hundred and forty-eight consecutive new patients presenting to 7 private Rheumatology practices across Australia were enrolled. Using a smartphone application, each patient had photographs taken of their hands, completed a brief 9-part questionnaire, and had a single examination result (wrist irritability) recorded. The Rheumatologist diagnosis was entered following a 45-minute consultation. Multiple machine learning models were applied to both the photographic and survey/examination results, to generate a screening outcome for the primary diagnoses of osteoarthritis, rheumatoid and psoriatic arthritis.

resultsThe combined algorithms in the application performed well in identifying and discriminating between different forms of hand arthritis. The algorithms were able to predict rheumatoid arthritis with accuracy, precision, recall and specificity of 85.1, 80.0, 88.1 and 82.7% respectively. The corresponding results for psoriatic arthritis were 95.2, 76.9, 90.9 and 95.8%, and for osteoarthritis were 77.4, 78.3, 80.6 and 73.7%. The results were maintained when each contributor was excluded from the analysis. The median time to capture all data across the group was 2 minutes and 59 seconds.

conclusionsThis multicentre study confirms the results of the pilot study, and indicates that the performance of the screening tool is maintained across a group of different Rheumatologists. The smartphone application can provide a screening result from a combination of machine-learning algorithms applied to hand images and patient symptom responses. This could be used to assist primary care physicians in the assessment of patients presenting with hand arthritis, and has the potential to improve the clinical assessment and management of such patients.

Indexed as

Arthritis, PsoriaticOsteoarthritisRheumatologyHumansPilot ProjectsSmartphoneArtificial intelligenceDiagnosisEarly arthritisMachine learningScreeningTelemedicine

Identifiers

PMID35534813
PMCPMC9081322
OpenAlexW4229371882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.