Evidence map›Paper›PMID 35534585›Full record

ArticleMolecular biology reports2022

Comparison of genetic characteristics between captive and wild giant pandas based on 13 mitochondrial coding genes.

Yixin Zhu, Tao Deng, Maiju Qiao, Dan Tang, Xiaoyu Huang, Wenwen Deng, Huan Liu, Rengui Li, Tianming Lan

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Article in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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9 authors at 4 institutions in 1 country.

Yixin Zhu *State Key Laboratory of Agricultural Genomics, BGI-Shenzhen, Shenzhen, 518083, China.
Tao Deng *Key Laboratory of State Forestry and Grassland Administration (State Park Administration) on Conservation Biology of Rare Animals in the Giant Panda National Park, China Conservation and Research Center for the Giant Panda, Dujiangyan, 611830, China.
Maiju QiaoKey Laboratory of State Forestry and Grassland Administration (State Park Administration) on Conservation Biology of Rare Animals in the Giant Panda National Park, China Conservation and Research Center for the Giant Panda, Dujiangyan, 611830, China.
Dan TangKey Laboratory of State Forestry and Grassland Administration (State Park Administration) on Conservation Biology of Rare Animals in the Giant Panda National Park, China Conservation and Research Center for the Giant Panda, Dujiangyan, 611830, China.
Xiaoyu HuangKey Laboratory of State Forestry and Grassland Administration (State Park Administration) on Conservation Biology of Rare Animals in the Giant Panda National Park, China Conservation and Research Center for the Giant Panda, Dujiangyan, 611830, China.
Wenwen DengKey Laboratory of State Forestry and Grassland Administration (State Park Administration) on Conservation Biology of Rare Animals in the Giant Panda National Park, China Conservation and Research Center for the Giant Panda, Dujiangyan, 611830, China.
Huan LiuState Key Laboratory of Agricultural Genomics, BGI-Shenzhen, Shenzhen, 518083, China.
Rengui LiKey Laboratory of State Forestry and Grassland Administration (State Park Administration) on Conservation Biology of Rare Animals in the Giant Panda National Park, China Conservation and Research Center for the Giant Panda, Dujiangyan, 611830, China. 37183280@qq.com.
Tianming LanState Key Laboratory of Agricultural Genomics, BGI-Shenzhen, Shenzhen, 518083, China. lantianming@genomics.cn.
Chengdu Research Base of Giant Panda Breeding · CNState Forestry and Grassland Administration · CNBGI Group (China) · CNUniversity of Chinese Academy of Sciences · CN

Funding

Foundation of Key Laboratory of State Forestry and Grassland Administration (State Park Administration) on Conservation Biology of Rare Animals in the Giant Panda National Park KLSFGAGP2020.002Guangdong Provincial Key Laboratory of Genome Read and Write No. 2017B030301011Innovative Research Group Project of the National Natural Science Foundation of China 31972707
6 · The paper itself

Abstract

backgroundResearch on genetic diversity based on mitochondrial DNA of giant pandas mainly focused on a single marker or a few genes.

objectiveTo provide a more comprehensive assessment of the genetic diversity on giant pandas based on 13 mitochondrial protein coding genes.

methodsWe assembled 13 protein coding genes in the mitochondrial genome of the giant panda based on the whole genome sequencing data, including ND1, ND2, COX1, COX2, ATP8, ATP6, COX3, ND3, ND4L, ND4, ND5, ND6 and Cyt b.

resultsWe successfully obtained long sequence of 11,416 base pairs with all 13 genes for 110 giant panda individual, accounting for 67.93% in length of the mitochondrial reference genome. Haplotype diversity was 0.9518 ± 0.009 and nucleotide diversity (π) was 0.00157 ± 0.00014. We detected three new haplotypes, including GPC10 and GPC21 for the CR sequence and GPB12 for the Cyt b gene.

conclusionThese multi-gene sequences provided more genetic variable information to compare captive and wild giant panda population.

Indexed as

Genome, MitochondrialUrsidaeAnimalsBase CompositionCytochromes bDNA, MitochondrialGenes, MitochondrialSequence Analysis, DNACytochromes bDNA, MitochondrialGenetic diversityGiant pandaHaplotype diversityMitochondrial genome

Identifiers

PMID35534585
OpenAlexW4229439576

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