ReviewSeminars in cell & developmental biology2022
Hydrostatic pressure as a driver of cell and tissue morphogenesis.
Review in Seminars in cell & developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Flow-driven lumen remodeling and valve opening in the vas deferens.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Peristaltic locomotion with a twisted and bent spine in Dermophis mexicanus.The Journal of veterinary medical science · 2026Article
- Mechanics of compression-driven morphogenesis.Development (Cambridge, England) · 2026Review
- The role of geometry in morphogenesis.Development (Cambridge, England) · 2026Review
- Cell and tissue mechanics in 3-D organ morphogenesis: Insights from Drosophila pupal retina development.Developmental biology · 2026Review
- Hydrostatic pressure shapes and canalizes semicircular canal morphology to ensure vestibular function.bioRxiv : the preprint server for biology · 2026Article
- Piezo1-mediated mechanohydraulic control of cell volume drives cardiac morphogenesis.Science advances · 2026Article
- Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Permeability-driven pressure and cell proliferation control lumen morphogenesis in pancreatic organoids.Nature cell biology · 2026Article
- Microscale pressure measurements and optical coherence tomography reveal time-dependent biomechanical stages of ovulation in mice.iScience · 2025Article
- Regulation of epithelial tissue homeostasis by active transepithelial transport.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Organoids in respiratory virus research: advances and perspectives.Molecular biomedicine · 2025Review
- Organ-on-a-Chip: A Roadmap for Translational Research in Human and Veterinary Medicine.International journal of molecular sciences · 2025Review
- A developmental atlas of zebrafish gills links early vascular patterning to adult architecture.Development (Cambridge, England) · 2025Article
- Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells.Nature cell biology · 2025Article
- Hypotonic stimuli promote osteocyte dendrite formation by modulating actin dynamics via the TRPV4-CDC42 signaling pathway.Materials today. Bio · 2025Article
- Elevated hydrostatic pressure destabilizes VE-cadherin junctions in a time and shear stress dependent manner: An endothelium-on-chip study.APL bioengineering · 2025Article
- The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Mechanochemical patterning localizes the organizer of a luminal epithelium.Science advances · 2025Article
- Describing the musculature of mystacial pads in harbour seals (Phoca vitulina) using diceCT.Journal of anatomy · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Morphogenesis, the process by which tissues develop into functional shapes, requires coordinated mechanical forces. Most current literature ascribes contractile forces derived from actomyosin networks as the major driver of tissue morphogenesis. Recent works from diverse species have shown that pressure derived from fluids can generate deformations necessary for tissue morphogenesis. In this review, we discuss how hydrostatic pressure is generated at the cellular and tissue level and how the pressure can cause deformations. We highlight and review findings demonstrating the mechanical roles of pressures from fluid-filled lumens and viscous gel-like components of the extracellular matrix. We also emphasise the interactions and mechanochemical feedbacks between extracellular pressures and tissue behaviour in driving tissue remodelling. Lastly, we offer perspectives on the open questions in the field that will further our understanding to uncover new principles of tissue organisation during development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.