Evidence map›Paper›PMID 35534219›Full record

ArticleInvestigative and clinical urology2022

Relationships between erectile dysfunction, prostate cancer treatment type and inflatable penile prosthesis implantation.

Chan Shen, Kunj Jain, Tejash Shah, Eric Schaefer, Shouhao Zhou, Dennis Fried, Drew A Helmer, Hossein Sadeghi-Nejad

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Investigative and clinical urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. State of the science of sexual health among older cancer survivors: an integrative review.Journal of cancer survivorship : research and practice · 2025
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Chan ShenDepartment of Surgery, Division of Outcomes Research and Quality, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0001-5680-3134
Kunj JainDivision of Urology, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID 0000-0002-9430-7550
Tejash ShahDivision of Urology, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID 0000-0002-5301-8103
Eric SchaeferDepartment of Public Health Sciences, Division of Biostatistics and Bioinformatics, Penn State College of Medicine, Hershey, PA, USA.
Shouhao ZhouDepartment of Public Health Sciences, Division of Biostatistics and Bioinformatics, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0002-8124-5047
Dennis FriedWar-Related Injury & Illness Study Center, VA New Jersey Health Care System, East Orange, NJ, USA.ORCID 0000-0003-3517-0758
Drew A HelmerCenter for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey VA Medical Center, Houston, TX, USA.ORCID 0000-0003-0385-432X
Hossein Sadeghi-NejadWar-Related Injury & Illness Study Center, VA New Jersey Health Care System, East Orange, NJ, USA.ORCID 0000-0002-4032-8110
Pennsylvania State University · USRutgers, The State University of New Jersey · USVA New Jersey Health Care System · USDepartment of Public Health · MMMichael E. DeBakey VA Medical Center · US

Funding

Michael E. DeBakey VA Medical Center VA HSRD CIN 13-413
6 · The paper itself

Abstract

purposeThe prevalence of erectile dysfunction (ED) and the utilization of inflatable penile prosthesis (IPP) among prostate cancer patients are understudied. The aim of the study was to examine the relationships between ED, prostate cancer treatment type and IPP implantation in a national cohort. MATERIALS AND

methodsWe identified a retrospective cohort of Surveillance, Epidemiology, and End Results (SEER)-Medicare patients diagnosed with locoregional prostate cancer between 2006 and 2011 and treated with surgery or radiation. Chi-square tests were used to detect significant differences in ED rates as well as use of IPP among the subset with ED. Multivariable logistic regression was used to examine factors associated with the use of IPP.

resultsAmong 31,233 patients in our cohort, 10,334 (33.1%) received prostatectomy and 20,899 (66.9%) received radiation. ED within 5 years was significantly more common in the prostatectomy group relative to those the radiation group (65.3% vs. 33.8%, p<0.001). In the subset of 13,812 patients with ED, the radiation group had greater median time to ED diagnosis compared to the prostatectomy group (346 vs. 133 days, p<0.001). IPP implantation was more frequent for prostatectomy patients than for radiation patients (3.6% vs. 1.4%, p<0.001). Cancer treatment type, race, and marital status were significantly associated with IPP utilization.

conclusionsED is highly prevalent among prostate cancer patients, and IPP implantation is be underutilized. ED rates, time to ED diagnosis and utilization of IPP differed significantly by prostate cancer treatment type.

Indexed as

Erectile DysfunctionPenile ImplantationPenile ProsthesisProstatic NeoplasmsAgedHumansMaleMedicareRetrospective StudiesUnited StatesErectile dysfunctionPenile prosthesisProstate cancerProstatectomyRadiation

Identifiers

PMID35534219
PMCPMC9091830
OpenAlexW4226080104

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.