ReviewCurrent opinion in neurobiology2022
Preserved cortical somatotopic and motor representations in tetraplegic humans.
Review in Current opinion in neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Spinal Cord Injury 2.0: Bridging the Gap Between Neurobiology, Technology, and Hope in the Era of Precision Medicine.Stem cell reviews and reports · 2025Review
- Stable cortical body maps before and after arm amputation.Nature neuroscience · 2025Article
- Action-type mapping principles extend beyond evolutionarily conserved actions, even in people born without hands.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Evoking stable and precise tactile sensations via multi-electrode intracortical microstimulation of the somatosensory cortex.Nature biomedical engineering · 2025Article
- Effector specificity in human posterior parietal neurons and local field potentials during movement in virtual reality and online brain control.Journal of neural engineering · 2025Article
- Article
- [An emerging discipline: brain-computer interfaces medicine].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Review
- Flexible regulation of representations on a drifting manifold enables long-term stable complex neuroprosthetic control.bioRxiv : the preprint server for biology · 2023Article
- Tessellation of artificial touch via microstimulation of human somatosensory cortex.bioRxiv : the preprint server for biology · 2023Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
A rich literature has documented changes in cortical representations of the body in somatosensory and motor cortex. Recent clinical studies of brain-machine interfaces designed to assist paralyzed patients have afforded the opportunity to record from and stimulate human somatosensory, motor, and action-related areas of the posterior parietal cortex. These studies show considerable preserved structure in the cortical somato-motor system. Motor cortex can immediately control assistive devices, stimulation of somatosensory cortex produces sensations in an orderly somatotopic map, and the posterior parietal cortex shows a high-dimensional representation of cognitive action variables. These results are strikingly similar to what would be expected in a healthy subject, demonstrating considerable stability of adult cortex even after severe injury and despite potential plasticity-induced new activations within the same region of cortex. Clinically, these results emphasize the importance of targeting cortical areas for BMI control signals that are consistent with their normal functional role.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.