ArticleAmerican journal of respiratory and critical care medicine2022
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome Associated with COVID-19: An Emulated Target Trial Analysis.
Open access · hybridAbstract readMulticenter Study
In one paragraph
Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Reporting of Observational Studies Explicitly Aiming to Emulate Randomized Trials: A Systematic Review.JAMA network open · 2023Pooled it
- 60 years of ARDS and the evolution of extracorporeal lung support - from ECMO to ECCOIntensive care medicine · 2026Review
- Delayed intubation and 60-day mortality in severe COVID-19-associated acute respiratory failure in an emulated target trial using the OUTCOMEREA network.Scientific reports · 2026Article
- Design and Implementation of Observational Studies Emulating a Target Trial.JAMA network open · 2026Article
- Data-driven subphenotyping of severe ARDS patients requiring VV-ECMO.Frontiers in digital health · 2026Article
- Socioeconomic status and ECMO outcomes in severe ARDS.Annals of intensive care · 2026Article
- Adjusting for selection bias due to missing eligibility criteria in emulated target trials.American journal of epidemiology · 2025Article
- Impact of early PaCOAnnals of intensive care · 2025Article
- Review
- Extracorporeal life support for adult patients with ARDS.Intensive care medicine · 2025Review
- Advances in acute respiratory distress syndrome: focusing on heterogeneity, pathophysiology, and therapeutic strategies.Signal transduction and targeted therapy · 2025Review
- Lessons Learned From Awake ECMO Approach in Covid-19-Related Acute Respiratory Distress Syndrome - a Scoping Review.Therapeutics and clinical risk management · 2025Review
- Use of Extracorporeal Membrane Oxygenation for Patients with Coronavirus Disease 2019 Infection.Advances in surgery · 2024Review
- Respiratory extracorporeal membrane oxygenation : From rescue therapy to standard tool for treatment of acute respiratory distress syndrome?Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024Review
- Interhospital Transfer of Patients With Acute Respiratory Failure in the United States: A Scoping Review.Critical care explorations · 2024Article
- ECMO is associated with decreased hospital mortality in COVID-19 ARDS.Scientific reports · 2024Article
- Article
- Right ventricular injury in patients with COVID-19-related ARDS eligible for ECMO support: a multicenter retrospective study.Annals of intensive care · 2024Article
- Relationship between the Pre-ECMO and ECMO Time and Survival of Severe COVID-19 Patients: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Methodological biases in observational hospital studies of COVID-19 treatment effectiveness: pitfalls and potential.Frontiers in medicine · 2024Article
Corrections and comments
- Commented on by
Authors and funding
23 authors at 11 institutions in 3 countries.
David HajageSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP.
Alain CombesSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMRS) 1166, Institute of Cardiometabolism and Nutrition, Paris, France.
Christophe GuervillyMedecine Intensive Réanimation, Centre hospitalier Universitaire L'Hôpital Nord, Assistance Publique hôpitaux de Marseille, Marseille, France.
Guillaume LebretonSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMRS) 1166, Institute of Cardiometabolism and Nutrition, Paris, France.
Alain MercatDépartement de Médecine Intensive - Réanimation et Médecine Hyperbare, CHU d'Angers, Faculté de Santé, Université d'Angers, Angers, France.
Arthur PavotUniversité Paris-Saclay, AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Le Kremlin-Bicêtre, France.
Saad NseirMédecine Intensive-Réanimation, CHU Lille, Inserm U1285, University of Lille, CNRS, UMR 8576, Unité de Glycobiologie Structurale et Fonctionnelle, Lille, France.
Armand Mekontso-DessapAP-HP (Assistance Publique-Hôpitaux de Paris), Hôpitaux universitaires Henri Mondor, DMU Médecine, Service de Médecine Intensive Réanimation, INSERM Unité U955, Créteil, France.
Nicolas MongardonService d'Anesthésie-Réanimation Chirurgicale, Hôpitaux Universitaires Henri Mondor, DMU CARE, Assistance Publique-Hôpitaux de Paris, Inserm U955 équipe 3, Faculté de Santé, Université Paris-Est Créteil, Créteil, France.
Jean Paul MiraAssistance Publique des Hôpitaux de Paris, Groupe Hospitalier Universitaire de Paris Centre, Hôpital Cochin, Médecine Intensive Réanimation; Paris Descartes Sorbonne Paris Cité University, Paris, France; Department of Infection, Immunity and Inflammation, Cochin Institute, Inserm U1016, Paris, France.
Jean-Damien RicardUniversité de Paris, APHP, Hôpital Louis Mourier, DMU ESPRIT, Service de Médecine Intensive Réanimation, Colombes, France.
Alexandra BeurtonAP-HP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive et Réanimation (Département R3S), and Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.
Guillaume TachonService de Médecine Intensive Réanimation, Hôpital Foch, Suresnes, France.
Loay KontarDepartment of Intensive Care Medicine, CHU Amiens-Picardie, avenue Laennec, Amiens, France.
Christophe Le TerrierDivision of Intensive Care, Geneva University Hospitals, Geneva, Switzerland.
Jean Christophe RichardService de Médecine Intensive-Réanimation, Hôpital de la Croix-Rousse-Hospices Civils de Lyon, Lyon, France.
Bruno MégarbaneDepartment of Medical and Toxicological Critical Care, Lariboisière Hospital, APHP, INSERM UMRS-1144, Paris University, Paris, France.
Ruth H KeoghDepartment of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom; and.
Aurélien BelotInequalities in Cancer Outcomes Network, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Camille MaringeInequalities in Cancer Outcomes Network, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Clémence LeyratDepartment of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom; and.ORCID 0000-0002-4097-4577
Matthieu SchmidtSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMRS) 1166, Institute of Cardiometabolism and Nutrition, Paris, France.ORCID 0000-0002-2931-4412
COVID-ICU Investigators
Inserm · FRLondon School of Hygiene & Tropical Medicine · GBDélégation Paris 5 · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire d'Angers · FRCentre National de la Recherche Scientifique · FRHôpital de la Croix-Rousse · FRHôpital Foch · FRHôpital Louis-Mourier · FRHôpital Nord · FRUniversity of Geneva · CH
Funding
Cancer Research UK 18525Cancer Research UK 29018Cancer Research UK C7923/A29018Medical Research Council MR/S017968/1Medical Research Council MR/T032448/1
Abstract
PubMed holds no abstract for this paper.
Indexed as
COVID-19Extracorporeal Membrane OxygenationRespiratory Distress SyndromeAdultCohort StudiesHumansRetrospective StudiesTreatment Outcomeacute respiratory distress syndromeCOVID-19emulated target trialextracorporeal membrane oxygenationSARS-CoV-2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.