Evidence map›Paper›PMID 35532838›Full record

ArticleJournal of mathematical biology2022

Pedigree in the biparental Moran model.

Camille Coron, Yves Le Jan

Abstract read
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In one paragraph

Article in Journal of mathematical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Camille CoronUniversité Paris-Saclay, CNRS, Laboratoire de mathématiques d'Orsay, Orsay, 91405, France. camille.coron@universite-paris-saclay.fr.ORCID 0000-0002-0463-2166
Yves Le JanNYU, Université Paris-Saclay, CNRS, Laboratoire de mathématiques d'Orsay, Orsay, 91405, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our goal is to study the genetic composition of a population in which each individual has 2 parents, who contribute equally to the genome of their offspring. We use a biparental Moran model, which is characterized by its fixed number N of individuals. We fix an individual and consider the proportions of the genomes of all individuals living  n time steps later, that come from this individual. When n goes to infinity, these proportions all converge almost surely towards the same random variable. When N then goes to infinity, this random variable multiplied by N (i.e. the stationary weight of any ancestor in the whole population) converges in law towards the mixture of a Dirac measure in 0 and an exponential law with parameter 1/2, and the weights of several given ancestors are independent. This gives an explicit formula for the limiting (deterministic) distribution of all ancestors' weights.

Indexed as

GenomeModels, GeneticGenetics, PopulationHumansPedigreeAncestor’s genetic contributionBiparental Moran modelGenealogyk-particle Markov chainLarge population size limitPedigreeStationary distribution

Identifiers

PMID35532838
OpenAlexW4229377612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.