Evidence map›Paper›PMID 35532835›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022

Estimating the EQ-5D-5L value set for the Philippines.

Red Thaddeus D Miguel, Adovich S Rivera, Kent Jason G Cheng, Kim Rand, Fredrick Dermawan Purba, Nan Luo, Ma-Ann Zarsuelo, Anne Julienne Genuino-Marfori, Irene Florentino-Fariñas, Anna Melissa Guerrero and 1 more

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. EQ-5D-5L value set for Norway: a hybrid model using cTTO and DCE data.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Red Thaddeus D MiguelInstitute of Health Policy and Development Studies, National Institutes of Health, University of the Philippines Manila, Manila, Philippines.ORCID http://orcid.org/0000-0002-2635-7484
Adovich S RiveraInstitute for Public Health and Management, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. adovichrivera2021@u.northwestern.edu.ORCID http://orcid.org/0000-0003-2533-0818
Kent Jason G ChengSocial Science Department, Maxwell School of Citizenship and Public Affairs, Syracuse University, Syracuse, NY, USA.ORCID http://orcid.org/0000-0002-8931-4086
Kim RandHealth Services Research Centre, Akershus University Hospital, Lorenskog, Norway.ORCID http://orcid.org/0000-0001-7692-4099
Fredrick Dermawan PurbaDepartment of Developmental Psychology, Faculty of Psychology, Universitas Padjadjaran, Jatinangor, Indonesia.ORCID http://orcid.org/0000-0002-7336-3043
Nan LuoSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0001-7980-6979
Ma-Ann ZarsueloInstitute of Health Policy and Development Studies, National Institutes of Health, University of the Philippines Manila, Manila, Philippines.
Anne Julienne Genuino-MarforiDepartment of Health-Pharmaceutical Division, Manila, Philippines.
Irene Florentino-FariñasDepartment of Health-Pharmaceutical Division, Manila, Philippines.
Anna Melissa GuerreroDepartment of Health-Pharmaceutical Division, Manila, Philippines.
Hilton Y LamInstitute of Health Policy and Development Studies, National Institutes of Health, University of the Philippines Manila, Manila, Philippines.ORCID http://orcid.org/0000-0003-4042-5997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Philippines has recommended the use of Quality-Adjusted Life Years (QALYs) in government health technology assessments (HTA). We aimed to develop a value set for the EQ-5D-5L based on health preferences of the healthy general adult population in the Philippines.

methodsHealthy, literate adults were recruited from the Philippine general population with quota targets based on age, sex, administrative region, type of residence, education, income, and ethnolinguistic groups. Each participant's preference was elicited by completing Composite Time Trade-Off (C-TTO) and Discrete Choice Experiment (DCE) tasks. Tasks were computer-assisted using the EuroQol Valuation Technology 2.0. To estimate the value set, we explored 20- and 8-parameter models that either use c-TTO-only data or both c-TTO and DCE (also called hybrid models). Final model choice was guided by principles of monotonicity, out-of-sample likelihood, model fit, and parsimony.

resultsWe recruited 1000 respondents with demographic characteristics that approximate the general population such as 49.6% Female, 82% Roman Catholic, 40% in urban areas, and 55% finished high school. None of the 20-parameter models demonstrated monotonicity (logical worsening of coefficients with increasing severity). From the 8-parameter models, the homoscedastic TTO-only model exhibited the best fit. From this model, mobility and pain/ discomfort had the highest effect on utilities.

conclusionThe selected model for representing the Philippine general population preferences for EQ-5D-5L health states was an 8-parameter homoscedastic TTO-only model. This value set is recommended for use in QALY calculations in support of HTA-informed coverage decisions in the Philippines.

Indexed as

Patient PreferenceQuality of LifeAdultChoice BehaviorFemaleHealth StatusHumansMalePhilippinesSurveys and QuestionnairesDeveloping countriesEQ-5D-5LHybrid mathematical modelingQALYUtility weights

Identifiers

PMID35532835
PMCPMC9356948

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.