Evidence map›Paper›PMID 35532560›Full record

ArticleAsian journal of andrology

Evaluation of inactivated COVID-19 vaccine on semen parameters in reproductive-age males: a retrospective cohort study.

Hong Zhu, Xiao Wang, Feng Zhang, Yong Zhu, Mei-Rong Du, Zhi-Wen Tao, Can Sun, Hai-Tao Ma, Ya-Dong Li, Guo-Qing Liang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. SARS-CoV-2 and male infertility: from short- to long-term impacts.Journal of endocrinological investigation · 2023
    Review
  12. Review
  13. SARS-CoV-2, fertility and assisted reproduction.Human reproduction update · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hong ZhuHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Xiao WangHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Feng ZhangHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Yong ZhuHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Mei-Rong DuShanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Zhi-Wen TaoHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Can SunHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Hai-Tao MaHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Ya-Dong LiHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Guo-Qing LiangHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Jie RenHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Bai-Lan FengHuman Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Feng JiangDepartment of Andrology, Shanghai Ji Ai Genetics and IVF institute China-USA Center, Shanghai 200011, China.
Obstetrics and Gynecology Hospital of Fudan University · CNShangHai JiAi Genetics & IVF Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the coronavirus disease (COVID-19) epidemic, there have been concerns about the impact of vaccines on people's fertility, including the fertility of those who are currently preparing for pregnancy and those who might become pregnant in future. However, there is still a lack of research on the effect of the COVID-19 vaccine on male fertility, and it is not surprising that couples and donors have concerns regarding vaccination. In this study, a retrospective cohort study was conducted to examine semen quality before and after receipt of the inactivated COVID-19 vaccine. There were no statistically significant changes in semen parameters (volume, sperm concentration, progressive motility, and total progressive motile count) after two doses of vaccine (all P > 0.05). In summary, our study updates the most recent studies on the effects of the COVID-19 vaccine on male fertility, and the information from this study could be used to guide fertility recommendations for assisted reproductive technology (ART) patients and donors.

Indexed as

COVID-19Semen AnalysisCOVID-19 VaccinesFemaleHumansMalePregnancyRetrospective StudiesSemenSpermatozoaSperm CountSperm MotilityVaccinationVaccines, InactivatedCOVID-19 VaccinesVaccines, Inactivatedassisted reproductive technologycoronavirus disease vaccinemale fertilitysemen parameterssperm donation

Identifiers

PMID35532560
PMCPMC9491047
OpenAlexW4229451374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.