Evidence map›Paper›PMID 35532354›Full record

ArticleMicrobiology spectrum2022

Survival Characteristics and Transcriptomic Analyses Reveal the Adaptive Response of the Aquatic Pathogen Non-O1/O139 Vibrio cholerae to Starvation Stress.

Xiaojian Gao, Zirui Zhang, Qieqi Qian, Qiyun Chen, Shuwen Gu, Jie Li, Yingjie Zhang, Congcong Wu, Qun Jiang, Xiaojun Zhang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaojian GaoCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Zirui ZhangCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Qieqi QianCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Qiyun ChenCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Shuwen GuCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Jie LiCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Yingjie ZhangCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Congcong WuCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Qun JiangCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.
Xiaojun ZhangCollege of Animal Science and Technology, Yangzhou Universitygrid.268415.c, Yangzhou, China.ORCID 0000-0003-3480-3322
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-O1/O139 Vibrio cholerae is a pathogen of various aquatic organisms but requires major self-regulation to overcome environmental stress in the aquatic environment. However, its survival strategies under environmental stress are not well understood. The objective of this study was to describe the survival characteristics and changes in expression of stress resistance-related genes of non-O1/O139 V. cholerae after 6 months of starvation at room temperature. The results demonstrated that starved cells were still viable, exhibited shortened rods and shrinking surface, and maintained virulence to Macrobrachium rosenbergii. To investigate the changes in gene expression in non-O1/O139 V. cholerae under starvation stress, especially those involved in stress resistance, transcriptome profiles of starved and wild-type cells were determined. The differentially expressed genes (DEGs) in starved cells were identified, including 191 upregulated genes and 180 downregulated genes. Among these DEGs, the well-known stress resistance-related genes were upregulated significantly, including

Indexed as

CholeraVibrio choleraeVibrio InfectionsAnimalsTranscriptomeVirulencenon-O1/O139 V. choleraestarvationstress responsessurvivaltranscriptome

Identifiers

PMID35532354
PMCPMC9241822
OpenAlexW4229375043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.