Evidence map›Paper›PMID 35532216›Full record

ArticlemBio2022

Salmonella Facilitates Iron Acquisition through UMPylation of Ferric Uptake Regulator.

Haihong Jia, Nannan Song, Yue Ma, Fengyu Zhang, Yingying Yue, Weiwei Wang, Cuiling Li, Hui Li, Qi Wang, Lichuan Gu and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Protein-centric mechanisms of typhoidalFrontiers in cellular and infection microbiology · 2026
    Review
  3. Propionylation of Fis K32 inFuture microbiology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Haihong Jia *Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Nannan Song *Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Yue MaDepartment of Pathogen Biology, School of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Fengyu ZhangState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong Universitygrid.27255.37, Qingdao, China.
Yingying YueDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Weiwei WangDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Cuiling LiDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Hui LiDepartment of Pathogen Biology, School of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Qi WangDepartment of Pathogen Biology, School of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Lichuan GuState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong Universitygrid.27255.37, Qingdao, China.ORCID 0000-0002-8201-403X
Bingqing LiDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.ORCID 0000-0002-4322-3744
Shandong Provincial Hospital · CNShandong First Medical University · CNShandong University · CNNational Health and Family Planning Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron limitation is a universal strategy of host immunity during bacterial infection. However, the mechanisms by which pathogens antagonize host nutritional immunity have not been fully elucidated. Here, we identified a requirement for the UMPylator YdiU for this process in Salmonella. The expression of YdiU was dramatically induced by the metal starvation signal. The intracellular iron content was much lower in the Δ

Indexed as

Iron DeficienciesRepressor ProteinsAnimalsBacterial ProteinsGene Expression Regulation, BacterialIronSalmonellaBacterial ProteinsIronRepressor ProteinsFuriron metabolismSalmonellaUMPylationYdiU

Identifiers

PMID35532216
PMCPMC9239237
OpenAlexW4229375847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.