Evidence map›Paper›PMID 35532121›Full record

ArticleMicrobial genomics2022

Enterovirus D68 epidemic, UK, 2018, was caused by subclades B3 and D1, predominantly in children and adults, respectively, with both subclades exhibiting extensive genetic diversity.

Hannah C Howson-Wells, Theocharis Tsoleridis, Izzah Zainuddin, Alexander W Tarr, William L Irving, Jonathan K Ball, Louise Berry, Gemma Clark, C Patrick McClure

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Prospective use of wastewater surveillance for early detection of enterovirus D68 in community outbreaks among children, Niigata City, Japan, 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hannah C Howson-WellsClinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Theocharis TsoleridisSchool of Life Sciences, University of Nottingham, Nottingham, UK.
Izzah ZainuddinClinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Alexander W TarrSchool of Life Sciences, University of Nottingham, Nottingham, UK.
William L IrvingClinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Jonathan K BallSchool of Life Sciences, University of Nottingham, Nottingham, UK.
Louise BerryClinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Gemma ClarkClinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
C Patrick McClureSchool of Life Sciences, University of Nottingham, Nottingham, UK.
Nottingham University Hospitals NHS Trust · GBUniversity of Nottingham · GB

Funding

Medical Research Council MC_PC_20027Medical Research Council MR/S009434/1
6 · The paper itself

Abstract

Enterovirus D68 (EV-D68) has recently been identified in biennial epidemics coinciding with diagnoses of non-polio acute flaccid paralysis/myelitis (AFP/AFM). We investigated the prevalence, genetic relatedness and associated clinical features of EV-D68 in 193 EV-positive samples from 193 patients in late 2018, UK. EV-D68 was detected in 83 (58 %) of 143 confirmed EV-positive samples. Sequencing and phylogenetic analysis revealed extensive genetic diversity, split between subclades B3 (

Indexed as

Enterovirus D, HumanEnterovirus InfectionsEpidemicsAgedCentral Nervous System Viral DiseasesChildGenetic VariationHumansMyelitisNeuromuscular DiseasesPhylogenyUnited Kingdomenterovirusenterovirus 68enterovirus 68, humanEV-D68genetic epidemiologygenotypemolecular epidemiologyvirology

Identifiers

PMID35532121
PMCPMC9465064
OpenAlexW4229374426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.