Evidence map›Paper›PMID 35531926›Full record

ArticleBiometrics2023

Power analysis for cluster randomized trials with continuous coprimary endpoints.

Siyun Yang, Mirjam Moerbeek, Monica Taljaard, Fan Li

Open access · hybridAbstract read
In one paragraph

Article in Biometrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Siyun YangDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0003-2895-532X
Mirjam MoerbeekDepartment of Methodology and Statistics, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0001-5537-1237
Monica TaljaardClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Fan LiDepartment of Biostatistics, Yale School of Public Health, New Haven, Connecticut.ORCID 0000-0001-6183-1893
Duke University · USUniversity of Ottawa · CAUtrecht University · NLYale University · US

Funding

Training Core (I)U54AG063546 · NIA · BROWN UNIVERSITY · PI JASON H KARLAWISH · 2019 to 2026
$125.9M
NIA NIH HHS U54 AG063546NIA NIH HHS U54AG063546
6 · The paper itself

Abstract

Pragmatic trials evaluating health care interventions often adopt cluster randomization due to scientific or logistical considerations. Systematic reviews have shown that coprimary endpoints are not uncommon in pragmatic trials but are seldom recognized in sample size or power calculations. While methods for power analysis based on K (

Indexed as

Research DesignCluster AnalysisComputer SimulationLinear ModelsRandomized Controlled Trials as TopicSample Sizecoefficient of variationgeneral linear hypothesisintersection-union testmultivariate linear mixed modelsample size determinationunequal cluster size

Identifiers

PMID35531926
PMCPMC11321238
OpenAlexW4226487945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.