ArticleBrain and behavior2022
Circumferential wall enhancement with contrast ratio measurement in unruptured intracranial aneurysm for aneurysm instability.
Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Analysis of symptomatic brain aneurysms with three-dimensional aneurysm wall enhancement.Neurosurgical review · 2026Observational
- Beyond the Lumen: Role of High-Resolution Magnetic Resonance Vessel Wall Imaging in Assessing Intracranial Aneurysms-A Prospective Observational Study from North India.The Indian journal of radiology & imaging · 2026Article
- Circumferential Aneurysm Wall Enhancement Predicts Recanalization After Stent-Assisted Coiling in Small Unruptured Intracranial Aneurysms.Brain and behavior · 2025Article
- Integrated multidisciplinary approach to aneurysm hemodynamic analysis: numerical simulation,Frontiers in bioengineering and biotechnology · 2025Review
- Review
- Can Aneurysm Wall Radiomics Help Predict Rupture Risk?Stroke (Hoboken, N.J.) · 2023Article
- Circumferential wall enhancement with contrast ratio measurement in unruptured intracranial aneurysm for aneurysm instability.Brain and behavior · 2022Article
- Circular RNA hsa_circ_0007990 as a blood biomarker for unruptured intracranial aneurysm with aneurysm wall enhancement.Frontiers in immunology · 2022Article
- Neutrophil-to-Lymphocyte Ratio Is Associated With Circumferential Wall Enhancement of Unruptured Intracranial Aneurysm.Frontiers in neurology · 2022Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAneurysm wall enhancement on high-resolution vessel wall imaging (HR-VWI) may represent vessel wall inflammation for unruptured intracranial aneurysms (UIAs). Further evidence for the role of circumferential aneurysm wall enhancement (CAWE) in evaluating the instability of UIAs is required, especially in small aneurysms (<7 mm).
methodsWe analyzed patients with saccular UIAs who prospectively underwent HR-VWI on a 3.0 T MRI scanner in our center from September 2017 to August 2021. The presence of AWE was identified and quantitatively measured using the aneurysm-to-pituitary stalk contrast ratio (CRstalk) with maximal signal intensity value. The PHASES and ELAPSS scores were used to assess the risk of aneurysm rupture and growth. We evaluated the association of CAWE and CRstalk value with intracranial aneurysm instability.
resultsOne hundred patients with 109 saccular UIAs were included in this study. Eighty-three UIAs (76.1%) had a size smaller than 7 mm. PHASES and ELAPSS scores were significantly higher in UIAs with CAWE than in UIAs without CAWE (p < .01). The association of CAWE with PHASES and ELAPSS scores remained in small UIAs (<7 mm). The optimal cutoff value of CRstalk for CAWE was 0.5. PHASES and ELAPSS scores were significantly higher in UIAs with CRstalk ≥0.5 than in UIAs with CRstalk <0.5 (p < .01).
conclusionsCAWE on HR-VWI is a valuable imaging marker for aneurysm instability in UIAs. CRstalk value ≥0.5 may be associated with a higher risk of intracranial aneurysm rupture and growth.
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