Evidence map›Paper›PMID 35531659›Full record

ArticleJournal of clinical microbiology2022

Annotated Whole-Genome Multilocus Sequence Typing Schema for Scalable High-Resolution Typing of Streptococcus pyogenes.

A Friães, R Mamede, M Ferreira, J Melo-Cristino, M Ramirez

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Genomic analysis and clinical characteristics of a seasonal upsurge of Streptococcus pyogenes emm12.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Increase of macrolide resistance amongAntimicrobial agents and chemotherapy · 2025
    Article
  6. Genomic epidemiology ofMicrobiology spectrum · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Sustained increase of paediatric invasiveEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A Friães *Instituto de Microbiologia, Instituto de Microbiologia Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
R Mamede *Instituto de Microbiologia, Instituto de Microbiologia Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
M FerreiraInstituto de Microbiologia, Instituto de Microbiologia Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
J Melo-CristinoInstituto de Microbiologia, Instituto de Microbiologia Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
M RamirezInstituto de Microbiologia, Instituto de Microbiologia Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.ORCID 0000-0002-4084-6233

Funding

MEC | Fundação para a Ciência e a Tecnologia (FCT) 2020.08493.BDMEC | Fundação para a Ciência e a Tecnologia (FCT) LISBOA-01-0145-FEDER-016417
6 · The paper itself

Abstract

Streptococcus pyogenes is a major human pathogen with high genetic diversity, largely created by recombination and horizontal gene transfer, making it difficult to use single nucleotide polymorphism (SNP)-based genome-wide analyses for surveillance. Using a gene-by-gene approach on 208 complete genomes of S. pyogenes, a novel whole-genome multilocus sequence typing (wgMLST) schema was developed, comprising 3,044 target loci. The schema was used for core-genome MLST (cgMLST) analyses of previously published data sets and 265 newly sequenced draft genomes with other molecular and phenotypic typing data. Clustering based on cgMLST data supported the genetic heterogeneity of many

Indexed as

Genome-Wide Association StudyStreptococcus pyogenesDisease OutbreaksElectrophoresis, Gel, Pulsed-FieldGenome, BacterialHumansMultilocus Sequence Typingbioinformaticsgenomicsgroup A Streptococcusmolecular epidemiologymolecular subtypingoutbreakpopulation geneticsStreptococcus pyogenessurveillance studiestyping

Identifiers

PMID35531659
PMCPMC9199402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.