Evidence map›Paper›PMID 35531652›Full record

ArticleChirality2022

2-O-Acetyl-3,4,5,6-tetra-O-benzyl-d-myo-inosityl diphenylphosphate: A new useful intermediate to inositol phosphate and phospholipids.

Sara Sangiorgio, Mattia Cambò, Riccardo Semproli, Daniela Ubiali, Giovanna Speranza, Marco Rabuffetti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chirality, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara SangiorgioDepartment of Chemistry, University of Milan, Milan, Italy.
Mattia CambòDepartment of Chemistry, University of Milan, Milan, Italy.
Riccardo SemproliDepartment of Drug Sciences, University of Pavia, Pavia, Italy.
Daniela UbialiDepartment of Drug Sciences, University of Pavia, Pavia, Italy.
Giovanna SperanzaDepartment of Chemistry, University of Milan, Milan, Italy.
Marco RabuffettiDepartment of Chemistry, University of Milan, Milan, Italy.ORCID 0000-0003-2089-1333

Funding

Cariplo Foundation 2017-0978Innovhub-SSI
6 · The paper itself

Abstract

Inositol phosphates and inositol phospholipids are ubiquitous in biochemistry and play a central role in cell signaling and regulation events. For this reason, their synthesis has attracted widespread interest. This paper describes the preparation of a new optically active inositol phosphate derivative, 2-O-acetyl-3,4,5,6-tetra-O-benzyl-d-myo-inosityl diphenylphosphate (6), and its characterization by spectroscopic methods. Compound (6) represents a useful intermediate for the preparation of inositol phosphate and phospholipids, in particular of glycerophosphoinositol (GPI), a natural anti-inflammatory agent.

Indexed as

Inositol PhosphatesPhospholipidsStereoisomerismInositol PhosphatesPhospholipidsanti-inflammatory activitydesymmetrizationl-camphor dimethyl acetalmyo-inositol phosphatemyo-inositol phospholipids

Identifiers

PMID35531652
PMCPMC9542212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.