Evidence map›Paper›PMID 35531589›Full record

ArticleAdvanced functional materials2020

Magnetothermal Multiplexing for Selective Remote Control of Cell Signaling.

Junsang Moon, Michael G Christiansen, Siyuan Rao, Colin Marcus, David C Bono, Dekel Rosenfeld, Danijela Gregurec, Georgios Varnavides, Po-Han Chiang, Seongjun Park and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced functional materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Magnetoelectric nanoparticles shape modulates their electrical output.Frontiers in bioengineering and biotechnology · 2023
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Junsang MoonDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Michael G ChristiansenDepartment of Health Sciences and Technology, Swiss Federal Institute of Technology, 8093 Zürich, Switzerland.
Siyuan RaoResearch Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Colin MarcusDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
David C BonoDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Dekel RosenfeldResearch Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Danijela GregurecResearch Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Georgios VarnavidesDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Po-Han ChiangResearch Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Seongjun ParkResearch Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Polina AnikeevaDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Funding

Multi-Site Non-Invasive Magnetothermal Excitation and Inhibition of Deep Brain StructuresR01MH111872 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANIKEEVA, POLINA O, PRALLE, ARND · 2016 to 2019
$3.6M
Magnetic Modulation on Targeted Neural Circuits in AutismR00MH120279 · NIMH · UNIVERSITY OF MASSACHUSETTS AMHERST · PI RAO, SIYUAN · 2021 to 2023
$747k
Magnetic Modulation on Targeted Neural Circuits in AutismK99MH120279 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI RAO, SIYUAN · 2019 to 2020
$164k
NIMH NIH HHS K99 MH120279NIMH NIH HHS R00 MH120279NIMH NIH HHS R01 MH111872
6 · The paper itself

Abstract

Magnetic nanoparticles have garnered sustained research interest for their promise in biomedical applications including diagnostic imaging, triggered drug release, cancer hyperthermia, and neural stimulation. Many of these applications make use of heat dissipation by ferrite nanoparticles under alternating magnetic fields, with these fields acting as an externally administered stimulus that is either present or absent, toggling heat dissipation on and off. Here, we motivate and demonstrate an extension of this concept, magnetothermal multiplexing, in which exposure to alternating magnetic fields of differing amplitude and frequency can result in selective and independent heating of magnetic nanoparticle ensembles. The differing magnetic coercivity of these particles, empirically characterized by a custom high amplitude alternating current magnetometer, informs the systematic selection of a multiplexed material system. This work culminates in a demonstration of magnetothermal multiplexing for selective remote control of cellular signaling

Indexed as

AC magnetometercellular signaling controlmagnetic nanoparticlemultiplexed magnetothermal controlselective nanoparticle heating

Identifiers

PMID35531589
PMCPMC9075680

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.