Evidence map›Paper›PMID 35531326›Full record

ArticleFrontiers in cellular and infection microbiology2022

Presence of Phylloquinone in the Intraerythrocytic Stages of

Rodrigo A C Sussmann, Heloisa B Gabriel, Alejandro García Ríos, Danielle S Menchaca Vega, Lydia F Yamaguchi, Antonio Doménech-Carbó, Gerardo Cebrián-Torrejón, Emilia A Kimura, Massuo J Kato, Ignasi Bofill Verdaguer and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 4 countries.

Rodrigo A C SussmannDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Heloisa B GabrielDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Alejandro García RíosLaboratory of Environmental Chemistry and Metalopharmaceuticals, Institute of Chemistry at the University of São Paulo, São Paulo, Brazil.
Danielle S Menchaca VegaDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Lydia F YamaguchiDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.
Antonio Doménech-CarbóDepartament of Analytic Chemistry, Facultat de Química, Universitat de València, Valencia, Spain.
Gerardo Cebrián-TorrejónLaboratoire Connaissance et Valorisation Equipes d'Accueil (COVACHIM-M2E EA) 3592, Université des Antilles, Pointe-à-Pitre Cedex, Pointe-à-Pitre, Guadeloupe, France.
Emilia A KimuraDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Massuo J KatoDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.
Ignasi Bofill VerdaguerDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Marcell CrispimDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Alejandro M KatzinDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Universidade de São Paulo · BRUniversitat de València · ESUniversité des Antilles · GP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is one of the most widespread parasitic diseases, especially in Africa, Southeast Asia and South America. One of the greatest problems for control of the disease is the emergence of drug resistance, which leads to a need for the development of new antimalarial compounds. The biosynthesis of isoprenoids has been investigated as part of a strategy to identify new targets to obtain new antimalarial drugs. Several isoprenoid quinones, including menaquinone-4 (MK-4/vitamin K2), α- and γ-tocopherol and ubiquinone (UQ) homologs UQ-8 and UQ-9, were previously detected in

Indexed as

AntimalarialsMalariaMalaria, FalciparumHumansPlasmodium falciparumVitamin K 1AntimalarialsVitamin K 1atovaquoneisoprenoidmalarianaphthoquinonephylloquinonephytolphytylplasmodium

Identifiers

PMID35531326
PMCPMC9069557
OpenAlexW4224256514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.