Evidence map›Paper›PMID 35531153›Full record

ArticleSaudi journal of biological sciences2022

In-vitro antioxidant, in-vivo anti-inflammatory, and acute toxicity study of Indonesian propolis capsule from

Siti Farida, Diah Kartika Pratami, Muhamad Sahlan, Dian Ratih Laksmitawati, Etin Rohmatin, Herbert Situmorang

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Siti FaridaDepartment of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia.
Diah Kartika PratamiFaculty of Pharmacy, Pancasila University, South Jakarta, Jakarta 12640, Indonesia.
Muhamad SahlanResearch Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java 16424, Indonesia.
Dian Ratih LaksmitawatiFaculty of Pharmacy, Pancasila University, South Jakarta, Jakarta 12640, Indonesia.
Etin RohmatinMidwifery Departement of Health Polytechnic Republic of Indonesia's Health Ministry Tasikmalaya, Tasikmalaya, West Java 46115, Indonesia.
Herbert SitumorangDepartment of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia.
University of Indonesia · IDPancasila University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Propolis is widely used as traditional medicine since ancient times. It was necessary to conduct the pre-clinical study because of its relevant curative properties. This study aimed to investigate in-vitro antioxidant, standardize quality parameters, study acute toxicity, and determine in-vivo anti-inflammatory. Three spectrophotometric methods were used to determine antioxidant activity. The standardization includes physical, chemical, and microbiological evaluation. Furthermore, an acute toxicity test was conducted using 20 female Sprague Dawley (SD) strain rats divided into 4 groups with different dose of propolis. The in vivo anti-inflammatory test was carried out using the carrageenan induction method on rats' soles. A total of 36 female SD rats were classified into 6 groups as follows, Group normal, negative control, diclofenac sodium, and three propolis groups (72; 144; and 288 mg/kg BW). The results demonstrated the IC

Indexed as

Acute toxicityAnti-inflammationAntioxidantPropolisTraditional medicine

Identifiers

PMID35531153
PMCPMC9073061
OpenAlexW4200465003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.