Evidence map›Paper›PMID 35530834›Full record

ArticleCureus2022

Isolated Otologic Involvement of IgG4 Related Disease: A Case Report and Review of Literature.

Hugh P Mallany, Vincent Anagnos, Tiffany Hwa, Tiffany Chao, Kathleen Montone, Steven Eliades

Abstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hugh P MallanyOtorhinolaryngology, University of New England, Biddeford, USA.
Vincent AnagnosOtorhinolaryngology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.
Tiffany HwaOtorhinolaryngology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.
Tiffany ChaoOtorhinolaryngology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.
Kathleen MontonePathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.
Steven EliadesOtorhinolaryngology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin G4 related disease (IgG4-RD) is a systemic autoimmune disease process that classically presents with multi-organ involvement; however isolated involvement of various structures within the body has also been described. Histopathologic examination is considered the gold standard for diagnosis. Glucocorticoids are well established as first-line treatment, but relapses are common, and consultation with rheumatology, immunology, and/or oncology teams is almost always warranted for proper medical management and disease maintenance. Given the relative infancy of IgG4-RD as an accepted diagnosis and the overall rarity of the disease, much still needs to be learned about this variable disease process. We present this case of isolated otologic and lateral skull base involvement of IgG4-RD to contribute to the understanding of this exceedingly rare clinical entity.

Indexed as

autoimmune diseasehearing lossigg4 related diseasemastoiditissigmoid sinus thrombosis

Identifiers

PMID35530834
PMCPMC9067345

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.