ReviewRSC advances2019
Advances in targeting and heterologous expression of genes involved in the synthesis of fungal secondary metabolites.
Review in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed.
- Structures and Biological Activities of Secondary Metabolites fromJournal of fungi (Basel, Switzerland) · 2024Review
- Secondary Metabolites Produced by the Blue-Cheese Ripening MoldJournal of fungi (Basel, Switzerland) · 2023Review
- Discovery and excavation of lichen bioactive natural products.Frontiers in microbiology · 2023Review
- Complementary Strategies to Unlock Biosynthesis Gene Clusters Encoding Secondary Metabolites in the Filamentous FungusJournal of fungi (Basel, Switzerland) · 2022Article
- Total Heterologous Biosynthesis of Fungal Natural Products inJournal of natural products · 2022Review
- Sorbicillinoids hyperproduction without affecting the cellulosic enzyme production in Trichoderma reesei JNTR5.Biotechnology for biofuels and bioproducts · 2022Article
- Investigating Fungal Biosynthetic Pathways Using Heterologous Gene Expression: Aspergillus nidulans as a Heterologous Host.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Characterization of cross-species transcription and splicing from Penicillium to Saccharomyces cerevisiae.Journal of industrial microbiology & biotechnology · 2021Article
- The Ku complex: recent advances and emerging roles outside of non-homologous end-joining.Cellular and molecular life sciences : CMLS · 2021Review
- Growth Inhibition of Phytopathogenic Fungi and Oomycetes by BasidiomycetePolish journal of microbiology · 2021Article
- A CRISPR/Cas9 Cleavage System for Capturing Fungal Secondary Metabolite Gene Clusters.Journal of microbiology and biotechnology · 2021Article
- Current State and Future Directions of Genetics and Genomics of Endophytic Fungi for Bioprospecting Efforts.Frontiers in bioengineering and biotechnology · 2021Review
- An Efficient Strategy for Obtaining Mutants by Targeted Gene Deletion inFrontiers in microbiology · 2021Article
- Deep learning approaches for natural product discovery from plant endophytic microbiomes.Environmental microbiome · 2021Review
- Article
- Bioprospecting Through Cloning of Whole Natural Product Biosynthetic Gene Clusters.Frontiers in bioengineering and biotechnology · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The revolutionary discovery of penicillin only marks the start of our exploration for valuable fungal natural products. Advanced genome sequencing technologies have translated the fungal genome into a huge reservoir of "recipes" - biosynthetic gene clusters (BGCs) - for biosynthesis. Studying complex fungal genetics demands specific gene manipulation strategies. This review summarizes the current progress in efficient gene targeting in fungal cells and heterologous expression systems for expressing fungal BGCs of fungal secondary metabolites.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.