ArticleCancer diagnosis & prognosis
Dysplastic Crypts in Asymmetric Branching in Ulcerative Colitis: A Preliminary Report.
Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
aimTo report the detection of dysplastic crypts in asymmetric branching (DCAB) in biopsies from patients with ulcerative colitis (UC). PATIENTS AND
methodsOne hundred consecutive endoscopic biopsies from patients with UC undergoing surveillance were reviewed.
resultsThree biopsy/cases showed DCAB. The frequency of DCAB varied from two in one case, three in another case, and five in the remaining case.
conclusionThe final outcome of DCAB is to generate two or more dysplastic asymmetric offspring-crypts. Repeated DCAB offspring formation, together with new DCAB, would boost the pool of dysplastic crypts, resulting in an exponential expansion of the mucosal area occupied by dysplasia in UC.
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