Evidence map›Paper›PMID 35530212›Full record

ArticleRSC advances2019

A gold nanoparticle strip for simultaneously evaluating FMDV immunized antibody level and discriminating FMDV vaccinated animals from infected animals.

Suzhen Yang, Yaning Sun, Jifei Yang, Yunchao Liu, Hua Feng, Gaiping Zhang

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Suzhen YangHenan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences Zhengzhou People's Republic of China zhanggaip@126.com.ORCID https://orcid.org/0000-0002-0084-820X
Yaning SunHenan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences Zhengzhou People's Republic of China zhanggaip@126.com.
Jifei YangHenan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences Zhengzhou People's Republic of China zhanggaip@126.com.
Yunchao LiuHenan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences Zhengzhou People's Republic of China zhanggaip@126.com.
Hua FengHenan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences Zhengzhou People's Republic of China zhanggaip@126.com.
Gaiping ZhangHenan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences Zhengzhou People's Republic of China zhanggaip@126.com.
Henan Academy of Agricultural Sciences · CNKerala Veterinary and Animal Sciences University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A gold nanoparticle strip was developed for rapidly evaluating FMDV type O antibody level and simultaneously discriminating FMDV vaccinated animals from infected animals. The strip was established depending on the colloidal gold nanoparticle labeling technique. Staphylococcal protein A colloidal gold nanoparticles were used as a probe. The epitope antigens of FMDV structural proteins and nonstructural proteins were dispensed on a nitrocellulose membrane as two test lines, respectively, and goat anti-pig antibody IgG was used as a control line. The assay was evaluated with FMDV immunized, infected sera and positive sera for another virus. The results showed the specificities of the T1 and T2 lines were 95.17% and 100% respectively. The sensitivity was in accordance with commercial ELISA kits. The coincidence rate of the new strip with 3ABC Mab-bELISA and LPB-ELISA was 95.5% and 93.13%, respectively. In summary, this experimental strip could provide a simple, inexpensive and rapid approach for onsite detection of FMDV type O antibody level and discrimination of FMDV vaccinated from infected animals without any expensive instrument.

Identifiers

PMID35530212
PMCPMC9072146
OpenAlexW2976861054

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.