ArticleRSC advances2019
Surface phosphonation treatment shows dose-dependent enhancement of the bioactivity of polyetheretherketone.
Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- UV-grafted polyitaconic acid functionalization of PEEK promotes osteoimmunomodulation and osseointegration with PI3K-AKT-associated autophagy regulation.Regenerative biomaterials · 2026Article
- Dose-dependent enhancement of in vitro osteogenic activity on strontium-decorated polyetheretherketone.Scientific reports · 2025Article
- Surface modification of polyetheretherketone for boosted osseointegration: A review.Biomaterials translational · 2025Review
- Alendronate as Bioactive Coating on Titanium Surfaces: An Investigation of CaP-Alendronate Interactions.Materials (Basel, Switzerland) · 2024Article
- Evaluation of High-Performance Polyether Ether Ketone Polymer Treated with Piranha Solution and Epigallocatechin-3-Gallate Coating.BioMed research international · 2024Article
- Mechanical performance and bioactivation of 3D-printed PEEK for high-performance implant manufacture: a review.Progress in biomaterials · 2023Review
- Surface Treatments of PEEK for Osseointegration to Bone.Biomolecules · 2023Review
- Improving Surface Properties of PEEK for Dental Applications by Using Piranha Solution.International journal of dentistry · 2023Article
- Surface Modifications of Poly(Ether Ether Ketone) via Polymerization Methods-Current Status and Future Prospects.Materials (Basel, Switzerland) · 2020Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyetheretherketone (PEEK) is a promising alternative for biomedical metallic implants in orthopedic and dental applications because its elastic modulus is similar to that of bone. However, PEEK is a bioinert material that cannot be integrated with host bone. Our previous study showed surface phosphonation enhanced the osteogenic activity of PEEK. The purpose of this study was to evaluate the effect of the density of phosphonate groups on the bioactivity of PEEK. X-ray photoelectron spectroscopy and water contact angle measurement confirmed the successful grafting of different densities of phosphonate groups to the PEEK surface using a one-step ultraviolet-initiated graft polymerization method. Atomic force microscopy revealed that the surface treatment did not significantly alter the surface topography and roughness.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.