Evidence map›Paper›PMID 35530174›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Researching COVID-19 in progressive MS requires a globally coordinated, multi-disciplinary and multi-stakeholder approach-perspectives from the International Progressive MS Alliance.

Paola Zaratin, Brenda Banwell, Timothy Coetzee, Giancarlo Comi, Anthony Feinstein, Robert Hyde, Marco Salvetti, Kathryn Smith

Open access · goldAbstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 4 countries.

Paola ZaratinItalian Multiple Sclerosis Foundation, Genoa, Italy.ORCID https://orcid.org/0000-0001-8935-4670
Brenda BanwellDivision of Child Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Timothy CoetzeeNational Multiple Sclerosis Society, New York, NY, USA.ORCID https://orcid.org/0000-0002-3031-7549
Giancarlo ComiUniversità Vita Salute San Raffaele, Milan, Italy.
Anthony FeinsteinSunnybrook Research Institute and University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0002-0132-0909
Robert HydeBiogen International GMBH, International Progressive MS Alliance Industry Forum representative, Zürich, Switzerland.
Marco SalvettiDepartment of Neurosciences, Mental Health and Sensory Organs, Centre for Experimental Neurological Therapies (CENTERS), Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-0501-8803
Kathryn SmithInternational Progressive MS Alliance, Lyme, CT, USA.ORCID https://orcid.org/0000-0001-9558-9038
Associazione Italiana Sclerosi Multipla · ITBiogen (Switzerland) · CHChildren's Hospital of Philadelphia · USHealth Alliance International · USIstituto Neurologico Mediterraneo · ITNational Multiple Sclerosis Society · USSunnybrook Health Science Centre · CAVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The COVID-19 pandemic has reinforced the importance of research for the health of our society and highlighted the need for stakeholders of the health research and care continuum to form a collaborative and interdependent ecosystem. Objective: With the world still reeling from waves of the COVID-19 pandemic and adapting to the vaccine rollout at widely different rates, the International Progressive MS Alliance (hereafter Alliance) organized a meeting (April 2021) to consider how the Covid-19 pandemic impacts the health and well-being of people with progressive Multiple Sclerosis (MS). Methods: We invited the Alliance stakeholders and experts to present what they have learned about SARS-CoV-2 infection and progressive MS and to define future scientific priorities. Results: The meeting highlighted three priorities for additional focus: (1) the impact of Disease Modifying Therapies (DMTs) on the risk of COVID-19 and on the efficacy of COVID-19 vaccines in people with progressive MS; (2) the long-term impact of COVID-19 and COVID-19 vaccines on the biology of progressive MS; and (3) the impact on well-being of people with progressive MS. Conclusion: This paper's calls to action could represent a path toward a shared research agenda. Multi-stakeholder and long-term investigations will be required to drive and evolve such an agenda.

Indexed as

COVID-19 pandemicMultiple sclerosismulti-stakeholder agendasprogression

Identifiers

PMID35530174
PMCPMC9073122
OpenAlexW4225408553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.