ReviewBehavioural neurology2022
Shared Etiology in Autism Spectrum Disorder and Epilepsy with Functional Disability.
Review in Behavioural neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Healing from the Ocean: Targeting Shared Mechanisms in Autism and Epilepsy Using Algae-Derived Compounds.Marine drugs · 2026Review
- Insight into Haploinsufficiency of the ERBB4 Gene: Expanding the Spectrum of Associated Phenotypes.Journal of autism and developmental disorders · 2026Article
- Dim light at night disrupts the sleep-wake cycle and exacerbates abnormal EEG activity in Cntnap2 knockout mice: implications for autism spectrum disorders.Molecular autism · 2025Article
- Genetic Diagnostic Yield in Autism Spectrum Disorder (ASD) and Epilepsy Phenotypes in Children with Genetically Defined ASD.Journal of autism and developmental disorders · 2025Article
- Endophenotype Research in Epilepsy Across Time.Brain sciences · 2025Article
- Autism Spectrum Disorder: What Do We Know and Where Do We Go?Brain sciences · 2025Review
- Article
- Neurocognitive mechanisms underlying autism spectrum disorders: a literature review.Frontiers in psychiatry · 2025Review
- A missense mutation in theJournal of medicine and life · 2024Article
- Aging Well and Autism: A Narrative Review and Recommendations for Future Research.Healthcare (Basel, Switzerland) · 2024Review
- Evaluation of serum interleukin-17 A and interleukin-22 levels in pediatric patients with autism spectrum disorder: a pilot study.BMC pediatrics · 2024Article
- A novel approach for ASD recognition based on graph attention networks.Frontiers in computational neuroscience · 2024Article
- Treatment options in autism with epilepsy.Frontiers in child and adolescent psychiatry · 2024Article
- Is tuberous sclerosis complex-associated autism a preventable and treatable disorder?World journal of pediatrics : WJP · 2024Review
- Audiogenic Seizures and Social Deficits: No Aggravation Found in Krushinsky-Molodkina Rats.Biomedicines · 2023Article
- Role of gastrointestinal health in managing children with autism spectrum disorder.World journal of clinical pediatrics · 2023Review
- Autism Spectrum Disorder: Neurodevelopmental Risk Factors, Biological Mechanism, and Precision Therapy.International journal of molecular sciences · 2023Review
- A Literature Review of Similarities Between and Among Patients With Autism Spectrum Disorder and Epilepsy.Cureus · 2023Review
- Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders.Frontiers in pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autism spectrum disorders and epilepsies are heterogeneous human disorders that have miscellaneous etiologies and pathophysiology. There is considerable risk of frequent epilepsy in autism that facilitates amplified morbidity and mortality. Several biological pathways appear to be involved in disease progression, including gene transcription regulation, cellular growth, synaptic channel function, and maintenance of synaptic structure. Here, abnormalities in excitatory/inhibitory (E/I) balance ratio are reviewed along with part of an epileptiform activity that may drive both overconnectivity and genetic disorders where autism spectrum disorders and epilepsy frequently co-occur. The most current ideas concerning common etiological and molecular mechanisms for co-occurrence of both autism spectrum disorders and epilepsy are discussed along with the powerful pharmacological therapies that protect the cognition and behavior of patients. Better understanding is necessary to identify a biological mechanism that might lead to possible treatments for these neurological disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.