Evidence map›Paper›PMID 35530132›Full record

ArticleActa pharmaceutica Sinica. B2022

Peroxidase from foxtail millet bran exerts anti-colorectal cancer activity

Shuhua Shan, Jinping Niu, Ruopeng Yin, Jiangying Shi, Lizhen Zhang, Caihong Wu, Hanqing Li, Zhuoyu Li

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shuhua ShanInstitute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China.
Jinping NiuInstitute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China.
Ruopeng YinInstitute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China.
Jiangying ShiInstitute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China.
Lizhen ZhangSchool of Life Science, Shanxi University, Taiyuan 030006, China.
Caihong WuInstitute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China.
Hanqing LiSchool of Life Science, Shanxi University, Taiyuan 030006, China.
Zhuoyu LiInstitute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China.
Shanxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular targeted therapy has become an emerging promising strategy in cancer treatment, and screening the agents targeting at cancer cell specific targets is very desirable for cancer treatment. Our previous study firstly found that a secretory peroxidase of class III derived from foxtail millet bran (FMBP) exhibited excellent targeting anti-colorectal cancer (CRC) activity

Indexed as

CAC, colitis-associated carcinogenesisCDKs, cyclin-dependent kinasesCETSA, cellular thermal shift assayCo-IP, co-immunoprecipitationColorectal cancerCRC, colorectal cancercsGRP78csGRP78, cell surface glucose-regulated protein 78DCFH-DA, dichloro-dihydro-fluorescein diacetateEGFR, epidermal growth factor receptorER, endoplasmic reticulumFDA, U.S. Food and Drug AdministrationFMBPFMBP, peroxidase derived from foxtail millet branFoxtail millet branGRP78, glucose-regulated protein 78H&E, hematoxylin & eosinISM, isthminMPs, membrane proteinsNBD, the nucleotide binding domain of csGRP78PD-1, programmed death-1rGRP78, recombinant GRP78ROSROS, reactive oxygen speciesSBD, substrate-binding domain of csGRP78SPF, specific pathogen freeSTAT3STAT3, signal transducer and activator of transcription 3TRAIL, tumor necrosis factor-related apoptosis-inducing ligand

Identifiers

PMID35530132
PMCPMC9069399
OpenAlexW3205454912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.