Evidence map›Paper›PMID 35529875›Full record

ArticleFrontiers in immunology2022

STING Is Required in Conventional Dendritic Cells for DNA Vaccine Induction of Type I T Helper Cell- Dependent Antibody Responses.

Justin Theophilus Ulrich-Lewis, Kevin E Draves, Kelsey Roe, Megan A O'Connor, Edward A Clark, Deborah Heydenburg Fuller

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Harnessing innate immune pathways for therapeutic advancement in cancer.Signal transduction and targeted therapy · 2024
    Review
  9. Review
  10. STING Protein-Based In Situ Vaccine Synergizes CD4Advanced healthcare materials · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Justin Theophilus Ulrich-LewisDepartment of Microbiology, University of Washington, Seattle, WA, United States.
Kevin E DravesDepartment of Microbiology, University of Washington, Seattle, WA, United States.
Kelsey RoeDepartment of Immunology, University of Washington, Seattle, WA, United States.
Megan A O'ConnorDepartment of Microbiology, University of Washington, Seattle, WA, United States.
Edward A ClarkDepartment of Microbiology, University of Washington, Seattle, WA, United States.
Deborah Heydenburg FullerDepartment of Microbiology, University of Washington, Seattle, WA, United States.
University of Washington · US

Funding

Programming protective immunity by targeting antigens to the CD180 receptorR01AI052203 · NIAID · UNIVERSITY OF WASHINGTON · PI FULLER, DEBORAH H. · 2003 to 2019
$6.3M
Role of B cell activating factor (BAFF) in B cell responses and autoimmunityR01AI044257 · NIAID · UNIVERSITY OF WASHINGTON · PI GILTIAY, NATALIA V · 1999 to 2020
$3.7M
NIAID NIH HHS R01 AI044257NIAID NIH HHS R01 AI052203
6 · The paper itself

Abstract

DNA vaccines elicit antibody, T helper cell responses and CD8

Indexed as

Vaccines, DNAAnimalsAntibody FormationCD8-Positive T-LymphocytesDendritic CellsImmunoglobulin GMiceT-Lymphocytes, Helper-InducerImmunoglobulin GVaccines, DNAcGASdendritic cellsDNA vaccineSTINGtype I interferon

Identifiers

PMID35529875
PMCPMC9072870
OpenAlexW4224229384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.