Evidence map›Paper›PMID 35529731›Full record

ArticleRSC advances2019

A label-free aptamer-based biosensor for microRNA detection by the RNA-regulated fluorescence of malachite green.

Honghong Wang, Hui Wang, Mai Zhang, Yuting Jia, Zhengping Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Honghong WangSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China lzpbd@ustb.edu.cn.ORCID https://orcid.org/0000-0002-8535-5358
Hui WangSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China lzpbd@ustb.edu.cn.ORCID https://orcid.org/0000-0002-5116-1977
Mai ZhangSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China lzpbd@ustb.edu.cn.
Yuting JiaSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China lzpbd@ustb.edu.cn.
Zhengping LiSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China lzpbd@ustb.edu.cn.ORCID https://orcid.org/0000-0002-7573-8822
University of Science and Technology Beijing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) have been considered as promising molecular biomarkers for disease diagnosis, prognosis, as well as drug development. Herein, we wish to report a low background and label-free aptamer-based biosensor for miRNA assay by RNA-regulated fluorescence of malachite green (MG). In this biosensor-based strategy, target miRNA can specifically hybridize with the DNA extension template to form the T7

Identifiers

PMID35529731
PMCPMC9073149
OpenAlexW2981114868

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.