Evidence map›Paper›PMID 35529675›Full record

ArticleOncoimmunology2022

Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells.

Karthikeyan Subbarayan, Chiara Massa, Sandra Leisz, André Steven, Daniel Bethmann, Katharina Biehl, Claudia Wickenhauser, Barbara Seliger

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karthikeyan SubbarayanInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Chiara MassaInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Sandra LeiszInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.
André StevenInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.ORCID 0000-0003-4860-3399
Daniel BethmannInstitute of Pathology, Martin Luther University Halle-Wittenberg, Halle, Germany.ORCID 0000-0002-9582-025X
Katharina BiehlInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Claudia WickenhauserInstitute of Pathology, Martin Luther University Halle-Wittenberg, Halle, Germany.ORCID 0000-0002-1807-5575
Barbara SeligerInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.ORCID 0000-0002-5544-4958
Martin Luther University Halle-Wittenberg · DEFraunhofer Institute for Cell Therapy and Immunology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extracellular matrix component biglycan (BGN) plays an essential role in various physiological and pathophysiological processes. A deficient BGN expression associated with reduced immunogenicity was found in HER-2/neu-overexpressing cells. To determine whether BGN is suppressed by oncogene-driven regulatory networks, the expression and function of BGN was analyzed in murine and human BGN

Indexed as

Colorectal NeoplasmsFibroblastsAnimalsBiglycanHistocompatibility Antigens Class IHumansMiceRNA, MessengerTransfectionBiglycanHistocompatibility Antigens Class IRNA, Messengercolorectal carcinomaextracellular matrix proteinImmune escapeK-RASMHC class Ioncogeneproteoglycan

Identifiers

PMID35529675
PMCPMC9067524
OpenAlexW4285743260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.