Evidence map›Paper›PMID 35529456›Full record

ArticleFrontiers in nutrition2022

Potent Bioactive Compounds From Seaweed Waste to Combat Cancer Through Bioinformatics Investigation.

Kaushik Kumar Bharadwaj, Iqrar Ahmad, Siddhartha Pati, Arabinda Ghosh, Tanmay Sarkar, Bijuli Rabha, Harun Patel, Debabrat Baishya, Hisham Atan Edinur, Zulhisyam Abdul Kari and 2 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  13. Exploring the Therapeutic Potential ofMolecules (Basel, Switzerland) · 2024
    Article
  14. Article
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  16. Article
  17. Marine bioactive peptides with anticancer potential, a narrative review.International journal of biochemistry and molecular biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kaushik Kumar BharadwajDepartment of Bioengineering and Technology, Gauhati University, Guwahati, India.
Iqrar AhmadDivision of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, India.
Siddhartha PatiNatNov Bioscience Private Limited, Balasore, India.
Arabinda GhoshMicrobiology Division, Department of Botany, Gauhati University, Guwahati, India.
Tanmay SarkarDepartment of Food Processing Technology, Malda Polytechnic, West Bengal State Council of Technical Education, Govt. of West Bengal, Malda, India.
Bijuli RabhaDepartment of Bioengineering and Technology, Gauhati University, Guwahati, India.
Harun PatelDivision of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, India.
Debabrat BaishyaDepartment of Bioengineering and Technology, Gauhati University, Guwahati, India.
Hisham Atan EdinurSchool of Health Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Zulhisyam Abdul KariDepartment of Agricultural Sciences, Faculty of Agro-Based Industry, Universiti Malaysia Kelantan, Kelantan, Malaysia.
Muhammad Rajaei Ahmad Mohd ZainDepartment of Orthopaedics, School of Medical Sciences, Universiti Sains Malaysia, Kubang, Malaysia.
Wan Ishak Wan RosliSchool of Health Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The seaweed industries generate considerable amounts of waste that must be appropriately managed. This biomass from marine waste is a rich source of high-value bioactive compounds. Thus, this waste can be adequately utilized by recovering the compounds for therapeutic purposes. Histone deacetylases (HDACs) are key epigenetic regulators established as one of the most promising targets for cancer chemotherapy. In the present study, our objective is to find the HDAC 2 inhibitor. We performed top-down

Indexed as

HDAC 2MM-GBSAmolecular dockingmolecular dynamics simulationseaweed

Identifiers

PMID35529456
PMCPMC9075044

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.