Evidence map›Paper›PMID 35529447›Full record

ArticleFrontiers in pharmacology2022

Mosloflavone-Resveratrol Hybrid TMS-HDMF-5z Exhibits Potent

Seo-Yeon Kim, Ahmed H E Hassan, Kyung-Sook Chung, Su-Yeon Kim, Hee-Soo Han, Hwi-Ho Lee, Seang-Hwan Jung, Kwang-Young Lee, Ji-Sun Shin, Eungyeong Jang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Rational repurposing, synthesis,Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  5. Escaping ESKAPE resistance:Royal Society open science · 2023
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Seo-Yeon KimDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Ahmed H E HassanMedicinal Chemistry Laboratory, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Kyung-Sook ChungDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Su-Yeon KimDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Hee-Soo HanDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Hwi-Ho LeeDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Seang-Hwan JungDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Kwang-Young LeeDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Ji-Sun ShinDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Eungyeong JangDepartment of Internal Medicine, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Seolmin YoonDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, South Korea.
Yong Sup LeeDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, South Korea.
Kyung-Tae LeeDepartment of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Kyung Hee University · KRMansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TMS-HDMF-5z is a hybrid of the natural products mosloflavone and resveratrol. It was discovered to show potent inhibitory effects against lipopolysaccharide (LPS)-induced production of inflammatory mediators in RAW 264.7 macrophages. However, its mechanism of action is unknown. Hence this study aimed to demonstrate and explore

Indexed as

AP-1carrageenan-induced edemamacrophagesNF-κBTMS-HDMF-5z

Identifiers

PMID35529447
PMCPMC9068937
OpenAlexW4280492105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.