Evidence map›Paper›PMID 35529390›Full record

ArticleRSC advances2019

Nanopipette-assisted single cell metabolic glycan labeling.

Ze-Rui Zhou, Xiao-Yuan Wang, Jian Lv, Bin-Bin Chen, Yi-Bin Tang, Ruo-Can Qian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ze-Rui ZhouKey Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology Shanghai 200237 P. R. China ruocanqian@ecust.edu.cn +86 21 64250032.
Xiao-Yuan WangKey Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology Shanghai 200237 P. R. China ruocanqian@ecust.edu.cn +86 21 64250032.
Jian LvKey Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology Shanghai 200237 P. R. China ruocanqian@ecust.edu.cn +86 21 64250032.
Bin-Bin ChenKey Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology Shanghai 200237 P. R. China ruocanqian@ecust.edu.cn +86 21 64250032.
Yi-Bin TangKey Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology Shanghai 200237 P. R. China ruocanqian@ecust.edu.cn +86 21 64250032.
Ruo-Can QianKey Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology Shanghai 200237 P. R. China ruocanqian@ecust.edu.cn +86 21 64250032.ORCID https://orcid.org/0000-0002-1039-9866

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report a single cell glycan labeling strategy by combining nanoscale intracellular glass electrodes with bioorthogonal reaction. With the tip diameter less than 100 nm, the nanopipette electrode can be spatially controlled to inject artificial monosaccharides into single living cells with minimal invasion. The injection process can be precisely regulated by electroosmotic flow inside the nanopipette, and fluorescence labeling of sialic acid at single cell level is achieved.

Identifiers

PMID35529390
PMCPMC9072180

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.