Evidence map›Paper›PMID 35529299›Full record

ArticleCase reports in oncology

Ewing Sarcoma and Primitive Neuroectodermal Tumor of the Thoracic Esophagus: Case Report and Comprehensive Literature Review.

Jie Li, Pengfei Sun, Li Ma, Xianhua Min, Binqiang Ye, Yao Zhang, Weiwei Ta, Jiyun Deng, Xiangrong Cao, Chi Dong

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jie LiDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Pengfei SunDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Li MaDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Xianhua MinDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Binqiang YeDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Yao ZhangDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Weiwei TaDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Jiyun DengDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Xiangrong CaoDepartment of Radiotherapy, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Chi DongDepartment of Pathology, Second Hospital Affiliated to Lanzhou University, Lanzhou, China.
Lanzhou University Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ewing sarcoma and primitive neuroectodermal tumors (ES/PNETs) are rare tumors that belong to a family of round-cell neuroectodermally derived tumors, and their optimal treatment remains a great challenge. This study presented a case of ES/PNET, arising in the esophagus of a 21-year-old female patient presented with progressive dysphagia. Computed tomography and endoscopic ultrasonography showed a well-defined, submucosal solid mass in the superthoracic esophagus. The accurate diagnosis after surgery was obtained through immunohistochemistry and genetic studies, namely the CD99 immunopositivity as well as the EWSR1/FLI1 gene rearrangement associated with t(11;22)(q24;q12) in tumor cells. The patient underwent localized tumor resection followed by chemotherapy and chest radiotherapy. The patient is doing well with no evidence of tumor recurrence or metastasis 18 months after surgery. Although the esophagus is a rare site for ES/pPNET, we can speculate that the treatment protocol of ES/pPNET should include multi-agent chemotherapy, surgery, and local radiotherapy in order to improve the prognosis based on our report.

Indexed as

DiagnosisEsophagusExtraosseous Ewing sarcomaPrimitive neuroectodermal tumorTreatment

Identifiers

PMID35529299
PMCPMC9035948
OpenAlexW4220682576

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.