Evidence map›Paper›PMID 35529274›Full record

ArticleComputational and mathematical methods in medicine2022

Liraglutide Is Protective against Brain Injury in Mice with Febrile Seizures by Inhibiting Inflammatory Factors.

Xing Wang, Fei Yang, Liling Deng, Di Qiu, Yao Liu, Yang Kang

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xing WangDepartment of Pediatrics, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.
Fei YangDepartment of Pediatrics, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.
Liling DengDepartment of Pediatrics, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.
Di QiuDepartment of Pediatrics, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.
Yao LiuDepartment of Pediatrics, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.
Yang KangDepartment of Pediatrics, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China.ORCID https://orcid.org/0000-0002-4476-4438
Qiqihar Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The febrile seizure (FS) is a common disease in emergency pediatrics, and about 30% of patients are children aged between 6 months and 5 years. Therefore, we aim to observe the protective impact of liraglutide (LIR) on brain injury in mice with FS and to explore its relevant mechanisms. Male SD mice were selected, and the FS model was established by heat bath method. The behavioral score was performed on mice with Racine grading, and nerve cells in apoptosis in the hippocampus were determined by TUNEL. The content of glutamate was determined by ELISA. mRNA levels and protein expression of GLP-1, GLP-1R, IL-1

Indexed as

Brain InjuriesSeizures, FebrileAnimalsgamma-Aminobutyric AcidGlucagon-Like Peptide 1GlutamatesHumansInterleukin-6LiraglutideMaleMiceRatsRats, Sprague-DawleyTumor Necrosis Factor-alphagamma-Aminobutyric AcidGlucagon-Like Peptide 1GlutamatesInterleukin-6LiraglutideTumor Necrosis Factor-alpha

Identifiers

PMID35529274
PMCPMC9076292
OpenAlexW4225125183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.