Evidence map›Paper›PMID 35529231›Full record

ArticleRSC advances2019

Model Affitin and PEG modifications onto siRNA lipid nanocapsules: cell uptake and

Pauline Resnier, Elise Lepeltier, Anthea Lucrezia Emina, Natacha Galopin, Jérôme Bejaud, Stephanie David, Caroline Ballet, Thierry Benvegnu, Frédéric Pecorari, Igor Chourpa and 2 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 4 countries.

Pauline ResnierMINT, UNIV Angers, INSERM 1066, CNRS 6021, Université Bretagne Loire Angers France catherine.passirani@univ-angers.fr.
Elise LepeltierMINT, UNIV Angers, INSERM 1066, CNRS 6021, Université Bretagne Loire Angers France catherine.passirani@univ-angers.fr.ORCID https://orcid.org/0000-0002-7666-6453
Anthea Lucrezia EminaMINT, UNIV Angers, INSERM 1066, CNRS 6021, Université Bretagne Loire Angers France catherine.passirani@univ-angers.fr.
Natacha GalopinCRCINA, INSERM, Université d'Angers, Université de Nantes Nantes France.
Jérôme BejaudMINT, UNIV Angers, INSERM 1066, CNRS 6021, Université Bretagne Loire Angers France catherine.passirani@univ-angers.fr.
Stephanie DavidEA6295 - Nanomédicaments et Nanosondes, Université François-Rabelais de Tours, UFR de Pharmacie 31 avenue Monge F-37200 Tours France.
Caroline BalletUniv Rennes, Ecole Nationale Supérieure de Chimie de Rennes, CNRS, ISCR-UMR 6226 F-35000 Rennes France.
Thierry BenvegnuUniv Rennes, Ecole Nationale Supérieure de Chimie de Rennes, CNRS, ISCR-UMR 6226 F-35000 Rennes France.
Frédéric PecorariUMR CNRS 6299 - INSERM U892, CRCNA F-44007 Nantes France.
Igor ChourpaEA6295 - Nanomédicaments et Nanosondes, Université François-Rabelais de Tours, UFR de Pharmacie 31 avenue Monge F-37200 Tours France.ORCID https://orcid.org/0000-0003-2116-0735
Jean-Pierre BenoitMINT, UNIV Angers, INSERM 1066, CNRS 6021, Université Bretagne Loire Angers France catherine.passirani@univ-angers.fr.
Catherine PassiraniMINT, UNIV Angers, INSERM 1066, CNRS 6021, Université Bretagne Loire Angers France catherine.passirani@univ-angers.fr.ORCID https://orcid.org/0000-0001-6024-7839
Inserm · FRUniversité de Tours · FRUniversité Rennes 2 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant melanoma is an aggressive tumor, associated with the presence of local and/or distant metastases. The development of gene therapy by the use of small interfering RNA (siRNA) represents a promising new treatment. However, the protection of this biomolecule is necessary in order for it to be intravenously administrated, for example

Identifiers

PMID35529231
PMCPMC9070605
OpenAlexW2970473523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.