ArticleCrystal growth & design2022
A Digital Mechanistic Workflow for Predicting Solvent-Mediated Crystal Morphology: The α and β Forms of l-Glutamic Acid.
Article in Crystal growth & design, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- In Situ 3D Crystal Growth Measurement: Unravelling the Nature of Crystal Face-Specific Growth Rate Dispersion in α‑Form l‑Glutamic Acid.Industrial & engineering chemistry research · 2026Article
- Study of Batch and Semibatch Reactive Crystallization of l‑Glutamic Acid with aid of PATs, focusing on Polymorphism and Crystal Habit.Crystal growth & design · 2025Article
- Crystal Morphology and Associated Face-Specific Growth Kinetics of Tolfenamic Acid as a Function of Its Solution Crystallization Environment.Crystal growth & design · 2025Article
- Impact of aspect ratio and crystal size distribution of l-glutamic acid formed by cooling crystallization on drying characteristics.RSC advances · 2025Article
- Deconstructing 3D growth rates from transmission microscopy images of facetted crystals as capturedJournal of applied crystallography · 2024Article
- Automated Growth Rate Measurement of the Facet Surfaces of Single Crystals of the β-Form of l-Glutamic Acid Using Machine Learning Image Processing.Crystal growth & design · 2024Article
- Role of Molecular, Crystal, and Surface Chemistry in Directing the Crystallization of Entacapone Polymorphs on the Au(111) Template Surface.Crystal growth & design · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The solvent-mediated crystal morphologies of the α and β polymorphic forms of l-glutamic acid are presented. This work applies a digital mechanistically based workflow that encompasses calculation of the crystal lattice energy and its constituent intermolecular synthons, their interaction energies, and their key role in understanding and predicting crystal morphology as well as assessing the surface chemistry, topology, and solvent binding on crystal habit growth surfaces. Through a comparison between the contrasting morphologies of the conformational polymorphs of l-glutamic acid, this approach highlights how the interfacial chemistry of organic crystalline materials and their inherent anisotropic interactions with their solvation environments direct their crystal habit with potential impact on their further downstream processing behavior.
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Registered trials
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