Evidence map›Paper›PMID 35529052›Full record

ArticleJAC-antimicrobial resistance2022

Combination of phage therapy and cefiderocol to successfully treat

Patricia J Simner, Jerald Cherian, Gina A Suh, Yehudit Bergman, Stephan Beisken, Joseph Fackler, Martin Lee, Robert J Hopkins, Pranita D Tamma

Open access · goldAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Clearance of hypermutator XDRASM case reports · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Dietary Effects on the Gut Phageome.International journal of molecular sciences · 2024
    Review
  17. Article
  18. Article
  19. A Retrospective, Observational Study of 12 Cases of Expanded-Access Customized Phage Therapy: Production, Characteristics, and Clinical Outcomes.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Observational
  20. Bacteriophage-Antibiotic Combination Therapy againstAntibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Patricia J SimnerJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Jerald CherianJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Gina A SuhThe Mayo Clinic, Rochester, MN, USA.
Yehudit BergmanJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Stephan BeiskenAres Genetics, Vienna, Austria.
Joseph FacklerAdaptive Phage Therapeutics, Gaithersburg, MD, USA.
Martin LeeAdaptive Phage Therapeutics, Gaithersburg, MD, USA.
Robert J HopkinsJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Pranita D TammaJohns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-4143-6324
Johns Hopkins University · USMayo Clinic in Arizona · US

Funding

RESEARCH TRAINING IN MICROBIAL DISEASEST32AI007291 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JOEL N BLANKSON, Sara Elizabeth Cosgrove · 1986 to 2026
$9.1M
Modifiable Risk Factors for the Emergence of Resistance to Pseudomonas aeruginosaR21AI153580 · NIAID · JOHNS HOPKINS UNIVERSITY · PI TAMMA, PRANITA · 2021 to 2022
$479k
NIAID NIH HHS R21 AI153580NIAID NIH HHS T32 AI007291
6 · The paper itself

Abstract

Background: Patients and methods: We report the case of a 25-year-old male who experienced an accidental electrocution resulting in exposed calvarium in the left parieto-temporal region, complicated by a difficult-to-treat Results: WGS analysis identified a Conclusions: This report adds to the growing literature that phage therapy may be a safe and effective approach to augment antibiotic therapy for patients infected with drug-resistant pathogens. Furthermore, it highlights the importance of the GES β-lactamase family in contributing to inactivation of a broad range of β-lactam antibiotics in

Identifiers

PMID35529052
PMCPMC9071546
OpenAlexW4226292584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.